Some metabolic and haematological effects of oesophago-jejunostomy with by-pass of the stomach

Callender, Sheila T.; Witts, L. J.; Allison, P. R.; Gunning, Amy C.

doi:10.1136/gut.2.2.150

Cited by 15 publications

(3 citation statements)

References 9 publications

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“…We have noted similar findings after gastroenterostomy (Scott, Williams. and Clark, 1963) and comparable histological changes have been reported after gastric bypass procedures (Callender, Witts, Allison, and Gunning, 1961) and after total gastrectomy (Paulson and Harvey, 1954) implying that mechanical factors may be responsible (Deller, 1962).…”

Section: Discussionmentioning

confidence: 53%

Comparison of jejunal mucosa in post-gastrectomy states, idiopathic steatorrhoea, and controls using the dissecting microscope and conventional histological methods

Scott¹,

Williams²,

Clark³

1964

Gut

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EDITORIAL SYNOPSIS Jejunal biopsies from 24 patients with various post-gastrectomy states were compared with those from control patients and patients with idiopathic steatorrhoea. Minor histological changes, such as shortening and thickening of the villi, were frequently encountered in the control subjects, but the dissecting microscope showed that these were related to variations in villous shape. Similar changes in the villi were found in the post-gastrectomy patients, leaf-shaped villi and ridge formation being more common than was thought.

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Section: Discussionmentioning

confidence: 53%

Comparison of jejunal mucosa in post-gastrectomy states, idiopathic steatorrhoea, and controls using the dissecting microscope and conventional histological methods

Scott¹,

Williams²,

Clark³

1964

Gut

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“…Gastric bypass leaves the stomach essentially intact, yet vitamin B 12 deficiency may occur 7, 24, 77, 100. Gastric bypass reduced plasma vitamin B 12 levels 1 year later in approximately 30% of 20 patients despite a theoretically adequate oral intake and supplementation 100.…”

Section: Mechanisms Of Neurologic Injurymentioning

confidence: 99%

Neurologic complications after surgery for obesity

et al. 2005

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Bariatric surgical procedures are increasingly common. In this review, we characterize the neurologic complications of such procedures, including their mechanisms, frequency, and prognosis. Literature review yielded 50 case reports of 96 patients with neurologic symptoms after bariatric procedures. The most common presentations were peripheral neuropathy in 60 (62%) and encephalopathy in 30 (31%). Among the 60 patients with peripheral neuropathy, 40 (67%) had a polyneuropathy and 18 (30%) had mononeuropathies, which included 17 (94%) with meralgia paresthetica and 1 with foot drop. Neurologic emergencies including Wernicke's encephalopathy, rhabdomyolysis, and Guillain-Barré syndrome were also reported. In 18 surgical series reported between 1976 and 2004, 133 of 9996 patients (1.3%) were recognized to have neurologic complications (range: 0.08-16%). The only prospective study reported a neurologic complication rate of 4.6%, and a controlled retrospective study identified 16% of patients with peripheral neuropathy. There is evidence to suggest a role for inflammation or an immunologic mechanism in neuropathy after gastric bypass. Micronutrient deficiencies following gastric bypass were evaluated in 957 patients in 8 reports. A total of 236 (25%) had vitamin B(12) deficiency and 11 (1%) had thiamine deficiency. Routine monitoring of micronutrient levels and prompt recognition of neurological complications can reduce morbidity associated with these procedures.

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“…Patients with atrophic gastritis may sometimes absorb subnormal amounts ofvitamin B12 (Mollin et al 1957, Mollin 1959. These patients differ from patients with pernicious anemia in that absorption is sometimes improved by injection of carbachol or by giving the dose with a vitamin-B,2-free meal (Mollin et al 1957, Callender et al 1961, Deller et al 1961). The precise significance of the effect of carbachol or of the vitamin-Bl2free meal is uncertain.…”

Section: Radioactive Vitamin B12mentioning

confidence: 95%

Vitamin-B₁₂Metabolism in Man Using Cobalt 58 (⁵⁸Co) as a Tracer

Dl¹

1962

Proceedings of the Royal Society of Medicine

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Some metabolic and haematological effects of oesophago-jejunostomy with by-pass of the stomach

Cited by 15 publications

References 9 publications

Comparison of jejunal mucosa in post-gastrectomy states, idiopathic steatorrhoea, and controls using the dissecting microscope and conventional histological methods

Comparison of jejunal mucosa in post-gastrectomy states, idiopathic steatorrhoea, and controls using the dissecting microscope and conventional histological methods

Neurologic complications after surgery for obesity

Vitamin-B₁₂Metabolism in Man Using Cobalt 58 (⁵⁸Co) as a Tracer

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Some metabolic and haematological effects of oesophago-jejunostomy with by-pass of the stomach

Cited by 15 publications

References 9 publications

Comparison of jejunal mucosa in post-gastrectomy states, idiopathic steatorrhoea, and controls using the dissecting microscope and conventional histological methods

Comparison of jejunal mucosa in post-gastrectomy states, idiopathic steatorrhoea, and controls using the dissecting microscope and conventional histological methods

Neurologic complications after surgery for obesity

Vitamin-B12Metabolism in Man Using Cobalt 58 (58Co) as a Tracer

Contact Info

Product

Resources

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Vitamin-B₁₂Metabolism in Man Using Cobalt 58 (⁵⁸Co) as a Tracer