Comparison of jejunal mucosa in post-gastrectomy states, idiopathic steatorrhoea, and controls using the dissecting microscope and conventional histological methods

Abstract

EDITORIAL SYNOPSIS Jejunal biopsies from 24 patients with various post-gastrectomy states were compared with those from control patients and patients with idiopathic steatorrhoea. Minor histological changes, such as shortening and thickening of the villi, were frequently encountered in the control subjects, but the dissecting microscope showed that these were related to variations in villous shape. Similar changes in the villi were found in the post-gastrectomy patients, leaf-shaped villi and ridge formation being more common than was thought.

Jejunal Biopsy Findings in Healthy Young Men

“…Predominantly branched and fused villi have not been reported (Shiner & Doniach 1960, Rubin et al 1960, Scott et al 1964, Spiro et al 1964, Rubin & Dobbins 1965, Berg, Dahlqvist, Lindberg, Meeuwisse, Norden & Akerman 1967. Surface microscopy of jejunal biopsies from similar controls have shown mainly finger-shaped villi (Rubin et al 1960, Holmes, Hourihane & Booth 1961, Scott et al 1964, Rubin & Dobbins 1965, Berg et al 1967). However, predominantly leaf-shaped villi have been recorded in single cases (Ralston, Wood & Hughes 1960, Scott et al 1964, Berg et al 1967).…”

“…Surface microscopy of jejunal biopsies from similar controls have shown mainly finger-shaped villi (Rubin et al 1960, Holmes, Hourihane & Booth 1961, Scott et al 1964, Rubin & Dobbins 1965, Berg et al 1967). However, predominantly leaf-shaped villi have been recorded in single cases (Ralston, Wood & Hughes 1960, Scott et al 1964, Berg et al 1967). …”

“…whereas the mean values of total mucosal and glandular layer thicknesses were lower. As described previously (Scott et al 1964, Burhol & Myren 1966b. branched and fused villi histologically and leaf-shaped villi stereo-Scand J Gastroenterol Downloaded from informahealthcare.com by ThULB Jena on 11/19/14…”

Recovery of villous architecture in gluten enteropathy exacerbated by gastro-jejunal anastomosis

“…The jejunal mucosal histology following partial gastrectomy normally shows only minimal degrees of abnormality (Scott et al, 1964). We have examined the jejunal mucosal histology in forty-eight partial gastrectomy patients (Weir et al, 1962).…”

Small intestinal mucosal abnormalities in relatives of patients with dermatitis herpetiformis

“…The relatives in whom these tests were done were selected purely on the basis of their willingness to take part in the investigation. In view of the difference in the incidence of a convoluted mucosa in apparently normal people from different parts of the world (Baker, Ignatius, Mathan, Vaish, and Chacko, 1962;Banwell, Hutt, andTunnicliffe, 1964;England and O'Brien, 1966;Parkins, Eidelman, Perrin, and Rubin, 1966;Burhol and Myren, 1968) and indeed from different parts of Great Britain (Scott, Williams, and Clark, 1964;Salem and Truelove, 1965;Girdwood, Williams, McManus, Dellipiani, Delamore, and Kershaw, 1966;Marks and Shuster, 1970) the stereomicroscopic appearances in the relatives of the patients with dermatitis herpetiformis were compared with those in a control population from Newcastle upon Tyne (Marks and Shuster, 1970). This consisted of a series of coroner's necropsies on 48 people who died suddenly and in whom the incidence of a predominantly convoluted mucosa proved to be 8% (4/48).…”