This paper systematically reviews and critically examines the existing literature on well-being from the lens of entrepreneurship, in order to identify the state of the literature and propose future re-search agenda. The systematic literature review technique was employed to collect scientific re-search. All together eighty-two articles were included in the data analyses. The results suggest a diverse literature trying to link entrepreneurship and well-being, which indicates a growing but nascent area of research. The further inventory and critical evaluations of the existing research were categorised in terms of the research context, scope, results and conceptual rigours. Inherent from the systematic literature review technique, the scope of the existing literature covered in this paper may not be as comprehensive as a narrative literature review would have been. However, this article articulates the importance, timeliness and relevance of entrepreneurship for well-being in light of the increasing interests in both fields. It proposes a dynamic view of entrepreneurship and develops an ambitious research agenda, which addresses a number of emerging issues con-cerning well-being and entrepreneurship research.