Some Immunomodulating Effects of Ginger oil and Thyme oil in Rabbits

Abstract

This study was conducted to investigate the immunomodulating effects of the ginger and thyme oils (250 mg/kg BW, each) given orally for 21 successive days to rabbits vaccinated with rabbit hemorrhagic viral disease (RHVD). Two blood samples were collected at the 1 st , 2 nd , 3 rd , 7 tn , 14 th and 21 st days post drug and vaccine administration to study the effect of ginger and thyme oils on the innate immune response (phagocytic activity, serum lysozyme activity and nitric oxide production) and the humoral immune response (serum total proteins, determination of serum gamma globulins fraction using electrophoretic technique). The results revealed that ginger and thyme oils had immunostimulant effect on both the innate and humoral immune response as evidenced by significant increase in phagocytic activity, lysozyme activity, nitric oxide production, serum total proteins and gamma globulins in rabbits. Therefore, ginger oil and thyme oils are recommended as immunostimulant agents for rabbits in the dose of 250 mg/kg BW.

Effects of ginger extract and/or propolis extract on immune system parameters of vaccinated broilers

“…However, it has adverse side effects such as poor immune responses and causes incomplete sterilizing immunity ( El-Dabae et al, 2018 ) . Immunity is the body's defense mechanism against infections caused by microorganisms ( Shams et al, 2019 ). Many herbal extracts have antiviral properties as they have immunomodulatory effects ( Alagawany et al, 2019 ) , which are mediated by increasing the production of pro-inflammatory cytokines like IL-6 and IL-12 ( Trinchieri, 2003 ).…”