Some Aspects of Epidemiology and Etiopathogenesis of Metabolic Syndrome

Abdullozoda, S. M.

doi:10.25005/2074-0581-2020-22-4-580-594

Cited by 2 publications

(2 citation statements)

References 80 publications

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“…Актуальность. Метаболический синдром (МС), характеризованная Всемирной организацией здравоохранения как неинфекционная пандемия ХХI века продолжает оставаться одним из актуальных проблем современной медицины [1,3,10]. Это прежде всего обусловлено высокой частотой его распространенности и прогрессирующим ежегодным ростом почти во всех странах мира [5][6][7]10].…”

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“…В последние годы отмечается повышение интереса исследователей к изучению различных аспектов эпидемиологии и патогенеза МС. Это прежде всего обусловлено тем, что отмечается неуклонный рост числа населения имеющие различные компоненты МС [5,7,10], в том числе в условиях нашего региона [1][2][3] [5].…”

Section: Conclusion Metabolic Syndrome Is Detected In 72-135% Of the ...unclassified

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Prevalence of metabolic syndrome in Tajikistan

Gulov,

Abdullozoda,

Usmanova

et al. 2023

jour

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Objective. To study the prevalence of metabolic syndrome among the adult population of Tajikistan in the example of pilot districts.Material and methods. A total of 1304 individuals (718 women, 586 men, average age 41.1±13.6 years) from Dushanbe city and the pilot districts of Rudaki and Gissar were screened for metabolic syndrome without prior randomization. The diagnosis was based on clinical and laboratory indicators according to WHO (1999) and IDF (2005) criteria. All participants provided voluntary written consent to partake in the screening.Results and discussion. Using the WHO criteria, metabolic syndrome was identified in 94 (7.2%) people 38 (6.5%) men and 56 (7.8%) women. Hyperglycemia was detected in 97 (7.4%) respondents with a median fasting glucose level of 7.0 (6.8; 8.3) mmol/L. Increased waist to hip circumference ratio (n=174; 13.3%) was observed twice as often in women (n=117; 16.3%) compared to men (n=57; 9.7%) (p<0.001).Dyslipidemia in the form of increased triglycerides (n=372; 28.5%) or decreased high-density lipoproteins (HDL) (n=77; 5.9%) from reference values was identified in one in four participants.Arterial hypertension of varying severity was present in 20 (1.5%) respondents, with no significant difference between men (n=9; 1.54%) and women (n=11; 1.53%) (p>0.05). The median CAD and MAP in this group of respondents was 140.0 (130.0; 145.0) / 95.0 (90.0; 110.0) mmHg, with no discernible gender disparity.Based on the IDF (2005) criteria, metabolic syndrome was identified in 176 (13.5%) participants: 71 (12.1%) men and 105 (14.6%) women. As participant age increased, there was a corresponding rise in the occurrence of metabolic syndrome. Thus, among 18-44-year-old respondents (n=820), 39 (4.8%) had metabolic syndrome, among 45-59 year old (n=328) 36 (10.9%), among 60-74 year old (n=150) 17 (11.3%) and among 75-90 year old (n=6) 2 (33.3%).Conclusion. Metabolic syndrome is detected in 7.2-13.5% of the adult population. Young men and middleaged to elderly women are the most affected demographics. Due to the high prevalence of metabolic syndrome, it is necessary to strengthen organizational measures for its broad prevention among the general population by promoting a healthy lifestyle, healthy diet, and increasing physical activity.

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Section: Conclusion Metabolic Syndrome Is Detected In 72-135% Of the ...unclassified

Prevalence of metabolic syndrome in Tajikistan

Gulov,

Abdullozoda,

Usmanova

et al. 2023

jour

Self Cite

View full text Add to dashboard Cite

show abstract

Features of gestational period and perinatal outcomes in women with insulin resistance

Bаymatova

Oripova

Mulkamonova

et al. 2022

jour

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Aim. To study the course of pregnancy and perinatal outcomes in women with insulin resistance. Material and methods. A retrospective and prospective study of 102 women and their newborns who were born in the State Institution “Research Institute of Obstetrics, Gynecology, and Perinatology” for the period 2017-2019 was conducted. All pregnant women were divided into 3 groups according to the level of insulin resistance index (NOMA index). Group I - 42 pregnant women with developmental risk factors for diabetes with an insulin resistance index above 2.84. Group II consisted of 30 subjects with a NOMA index below 2.21, and Group III (n = 30) consisted of healthy pregnant women with a physiological course of pregnancy and labor. Results. Newborns born to women with a NOMA index above 2.84 (pathological insulin resistance) have a high incidence of perinatal complications: central nervous system defects, various degrees of asphyxia, hypotrophy, and immaturity. Conclusion. Insulin resistance in general affects pregnancy and has a negative impact on the course of pregnancy, causing a high incidence of complications such as threatened miscarriage, preeclampsia, chronic placental insufficiency and affecting perinatal outcomes.

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Some Aspects of Epidemiology and Etiopathogenesis of Metabolic Syndrome

Cited by 2 publications

References 80 publications

Prevalence of metabolic syndrome in Tajikistan

Prevalence of metabolic syndrome in Tajikistan

Features of gestational period and perinatal outcomes in women with insulin resistance

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