Some Applications of Statistics to Clinical Chemistry

Henry, Richard J.; Dryer, Robert L.

doi:10.1016/b978-1-4831-9685-5.50028-5

Cited by 26 publications

(7 citation statements)

References 11 publications

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“…In all cases the diagnosis recorded in the hospital records was used. Means, standard deviations, standard errors of the means and ranges were calculated according to the methods given by Moroney (1965), Henry and Dryer (1963), and Neumann (1968). For the purposes of computing a 'normal range', results were excluded that came from children with diseases in which an increased frequency of hyperuricaemia has been reported.…”

mentioning

confidence: 99%

Plasma uric acid levels in children.

Harkness¹,

Nicol²

1969

Archives of Disease in Childhood

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mentioning

confidence: 99%

Plasma uric acid levels in children.

Harkness¹,

Nicol²

1969

Archives of Disease in Childhood

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“…8 As iron, the limit of serum transferrin, the primary transport protein of iron, to tie and detoxify iron might be exceeded. 9,10 From that point, the non transferrin bound portion of iron inside plasma may advance age of free hydroxyl radicals, propagators of oxygen related damage 10 . Because of expanded serum ferritin fixation, results might be found as liver illnesses (disturbed liver compounds), pancreatic infections (impairement in glucose digestion) and heart diseases.…”

Section: Resultsmentioning

confidence: 99%

To study the level of serum liver enzymes (SGOT & SGPT) in multitransfused thalassemia major patients

Goyal¹,

Choudhary²

2020

IJMPO

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This study was conducted on 100 children with β -thalassemia major aged between 1-15 years being regularly transfused at Department of Pediatrics, M.G.M. Medical College, after taking the consent from the parents and explaining them the purpose and method of study. Result: Mean serum values of ferritin, SGOT, SGPT was found to be 6416.9 ± 1581.8 µg/l, 205.4 ± 46.3 u/l and 254.6 ± 71.7 u/l in patients who received more than 100 transfusions while it was 3784.2 ±1304 µg/l, 104.9 ± 52.9 u/l, and 131.5 ± 63.6 u/l respectively for those who receive more than 100 transfusions. Conclusion: Youngsters with >100 transfusions had serum values of liver enzymes and iron overload higher when contrasted with those with <100 transfusions. The distinction in values between the two gatherings was seen as exceptionally huge (p esteem <0.001) Mean serum estimations of ferritin, SGOT, SGPT was seen as 6416.9 ± 1581.8 µg/l, 205.4 ± 46.3 u/l and 254.6 ± 71.7 u/l in patients who got in excess of 100 transfusions while it was 3784.2 ±1304 µg/l, 104.9 ± 52.9 u/l, and 131.5 ± 63.6 u/l individually for the individuals who get less than 100 transfusions.

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“…The samples of feed offered, residues and faeces were analysed for proximate principles (AOAC 2000). Serum levels of glucose (Henry 1963), triglycerides (McGowan et al 1983), total cholesterol (Herbert et al 1984) and high density lipoprotein (HDL)-cholesterol (Siedel et al 1983), alkaline phosphatase (ALP, EC 3.1.3.1) (Kind and King 1954), alanine transaminase (AST, EC 2.6.1.2), aspartate transaminase (AST, EC 2.6.1.1) (Reitman and Frankel 1957) were determined using diagnostic kits (Span Diagnostics, Surat, India). The acid mineral extracts from feeds and faeces were prepared as per AOAC (2000) and mineral contents were estimated using inductively coupled plasma optical emission spectrophotometer following standard analytical conditions.…”

Section: Methodsmentioning

confidence: 99%

Boron supplementation provides hepato-protective effect and improves performance in Wistar rats fed calcium deficit diet

Bhasker

Gowda

Krishnamoorthy

et al. 2017

Indian J of Anim Sci

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This study was conducted to investigate the influence of boron (B) supplementation in rats fed diets with adequate and deficit calcium (Ca). A feeding trial of 90 days duration was conducted in 84 Wistar strain rats divided into 7 groups, viz. Normal-Ca (100%) basal diet (NC) and supplemented with B at 5 (NCB-5), 10 (NCB-10), 20 (NCB-20) and 40 (NCB-40) ppm levels; low-Ca (50%) diet (LC) and supplemented with 40 ppm B (LCB-40). During 80–85 days of feeding, a digestibility trial was conducted to record nutrient digestibility. Rats (8) from each group were sacrificed to collect blood and visceral organs to study biochemical parameters and histopathology. The average daily feed and water intake were similar among the dietary groups. Body weight gain was lower in rats fed LC diet and increased in the LCB-40 group. Nutrient (dry matter, crude protein, crude fat) digestibility was significantly improved with B-supplementation to NC diets. Serum levels of triglycerides, HDL-cholesterol and alanine transaminase were significantly lowered in B-supplemented groups. The levels of glucose, total cholesterol, alkaline phosphatase and aspartate transaminase in serum remained unaltered among the dietary groups. Degenerative changes were observed in the liver of rats fed Ca-deficient diets and were ameliorated with 40 ppm B supplementation. Results indicated that dietary supplementation of B in rats showed improved nutrient digestibility, growth and lowered serum levels of triglycerides, HDL-cholesterol and alanine transaminase. Hepatic tissue alterations due to lower Ca intake were ameliorated with B supplementation.

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Some Applications of Statistics to Clinical Chemistry

Cited by 26 publications

References 11 publications

Plasma uric acid levels in children.

Plasma uric acid levels in children.

To study the level of serum liver enzymes (SGOT & SGPT) in multitransfused thalassemia major patients

Boron supplementation provides hepato-protective effect and improves performance in Wistar rats fed calcium deficit diet

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