Somatostatin in the brain and the pituitary of some teleosts

Olivereau, Madeleine; Ollevier, Frans; Vandesande, Frans; Olivereau, Jacqueline

doi:10.1007/bf00217300

Cited by 57 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the European eel, SRIH-14 has been isolated and sequenced from the pancreas [27]; SRIH immunoreactive perikarya were observed in the brain, and fibers were shown in the pituitary on the basal lamina along GH cells [28]. …”

Section: Discussionmentioning

confidence: 99%

Long-Term Inhibitory Effects of Somatostatin and Insulin-Like Growth Factor 1 on Growth Hormone Release by Serum-Free Primary Culture of Pituitary Cells from European Eel (Anguilla anguilla)

et al. 1998

View full text Add to dashboard Cite

To investigate the ability of hypothalamic and peripheral factors to directly regulate growth hormone (GH) release in a primitive teleost, the European eel (Anguilla anguilla L.), we used primary cultures of dispersed pituitary cells. When cultured for 12 days in a serum-free medium, pituitary cells continuously released large amounts of GH, which exceeded the initial cellular content. Somatotropin-release inhibiting hormone (SRIH-14) dose-dependently inhibited GH release (EC₅₀ 0.75 nM) up to a maximal inhibitory effect of 95%. No desensitization of somatotropes to SRIH was observed over the 12 days of culture. Use of receptor subtype-selective SRIH agonists suggests the existence on eel somatotropes of SRIH receptor(s) related to the mammalian sst₂/sst₃/sst₅ class rather than to the sst₁/sst₄ class. Insulin-like growth factor 1 (IGF1) dose-dependently inhibited GH release (EC₅₀ 0.03 nM) up to a maximal inhibitory effect of 85%, without desensitization. IGF1 and IGF2 were equipotent in inhibiting GH release, whereas insulin was 1,000 times less active, suggesting the implication of a receptor related to the mammalian IGF type 1 receptor. These results indicate that eel somatotropes are active in vitro without any specific additional factors, and suggest the existence of a dominant inhibitory control of GH release in vivo. Two potential candidates for this chronic negative regulation are a neurohormone, SRIH and a circulating factor, IGF1. These data underline the early evolutionary origin of the molecular and functional SRIH-GH-IGF1 neuroendocrine axis in vertebrates.

show abstract

Section: Discussionmentioning

confidence: 99%

Long-Term Inhibitory Effects of Somatostatin and Insulin-Like Growth Factor 1 on Growth Hormone Release by Serum-Free Primary Culture of Pituitary Cells from European Eel (Anguilla anguilla)

et al. 1998

View full text Add to dashboard Cite

show abstract

“…The functional role of SOM in the control of GH secretion described for fish (Marchant et al, 1989; Lin et al, 1993) was related to the direct projection of SOM‐ir cells to the hypophysis (Kah et al, 1982; Olivereau et al, 1984; Batten et al, 1985; Grau et al, 1985; Moons et al, 1989), as was also suggested for anurans (Laquerrière et al, 1989). In contrast, urodeles and gymnophionans possess the intense SOM‐ir innervation of the median eminence and, most likely, carry out their role through the portal system as in amniotes (Dubois et al, 1974; Pelletier et al, 1974; Elde and Parsons, 1975; Epelbaum et al, 1977; Palkovits et al, 1980, 1982; Fasolo and Gaudino, 1982; Johansson et al, 1984; Alponti et al, 2006).…”

Section: Discussionmentioning

confidence: 74%

“…Although it is not the aim of the present study to deal extensively with the detailed distribution of SOM in other vertebrates, some comments will be made when needed to assess common vs. specific features of amphibians and, in particular, of Dermophis . For detailed information about the distribution of SOM immunoreactivity, the reader is referred to the mapping studies in cyclostomes (Nozaki and Gorbman, 1983; Wright, 1986; Yáñez et al, 1992), fish (Oliverau et al, 1984; Grau et al, 1985; Bonn and Köning, 1989; Chiba et al, 1989; Meurling and Rodríguez, 1990; Sas and Maler, 1991; Becerra et al, 1995; Vallarino et al, 1997; Trabucchi et al, 2002), reptiles (Fasolo and Gaudino, 1982; Bear and Ebner, 1983; Weindl et al, 1984; Alponti et al, 2006), birds (Shiosaka et al, 1981; Takatsuki et al, 1981; Blähser, 1984; Fontanesi et al, 1993; Trabucchi et al, 2003), and mammals (Elde and Parsons, 1975; Hoffman and Hayes, 1979; Beal et al, 1983; Johansson et al, 1984; Vincent et al, 1985; Cotter and Laemle, 1987; Desjardins and Parent, 1992).…”

Section: Discussionmentioning

confidence: 99%

Distribution of somatostatin‐like immunoreactivity in the brain of the caecilian Dermophis mexicanus (amphibia: Gymnophiona): Comparative aspects in amphibians

López

Moreno

Morona

et al. 2007

J of Comparative Neurology

View full text Add to dashboard Cite

The organization of the somatostatin-like-immunoreactive (SOM-ir) structures in the brain of anuran and urodele amphibians has been well documented, and significant differences were noted between the two amphibian orders. However, comparable data are not available for the third order of amphibians, the gymnophionans (caecilians). In the present study, we analyzed the anatomical distribution of SOM-ir cells and fibers in the brain of the gymnophionan Dermophis mexicanus. In addition, because of its known relationship with catecholamines in other vertebrates, double immunostaining for SOM and tyrosine hydroxylase was used to investigate this situation in the gymnophionan. Abundant SOM-ir cell bodies and fibers were widely distributed throughout the brain. In the telencephalon, pallial and subpallial cells were labeled, being most numerous in the medial pallium and amygdaloid region. Most of the SOM-ir neurons were found in the preoptic area and hypothalamus and showed a clear projection to the median eminence. Less conspicuously, SOM-ir structures were found in the thalamus, tectum, tegmentum, and reticular formation. Both SOM-ir cells and fibers were demonstrated in the spinal cord. The double-immunohistofluorescence technique revealed that catecholaminergic neurons and SOM-ir cells are largely intermingled in many brain regions but form totally separated populations. Many differences were found between the distribution of SOM-ir structures in Dermophis and that in anurans or urodeles. Some features were shared only with anurans, such as the abundant pallial SOM-ir cells, whereas others were common only to urodeles, such as the organization of the hypothalamohypophysial SOM-ir system. In addition, some characteristics were found only in Dermophis, such as the localization of the SOM-ir spinal cells and the lack of colocalization of catecholamines and SOM throughout the brain. Therefore, any conclusions concerning the SOM system in amphibians are incomplete without considering evidence for gymnophionans.

show abstract

“…Recent studies have revealed mammalian-like hypophyseal portal systems in other teleost species (Baskaran and Sathyanesan, 1992). Teleost GRF-and SS-hypothalamic neurosecretory pathways have been identified by immunohistochemistry (Pan, Liu and Bancroft, 1985;Marivoet, Moons and Vandesande, 1988;Olivereau et al, 1984). Both human and a recently purified carp GRF stimulate OH release in vitro (Luo et al, 1990;Le Bail et al, 1991;Vaughan et al, 1992) and in vivo (Peter et al, 1984).…”

Section: The Regulation Of Growth Hormonementioning

confidence: 99%

Biotechnology in Aquaculture, with Special Reference to Transgenic Salmon

Male¹,

Lorens

Nerland

et al. 1993

Biotechnology and Genetic Engineering Reviews

View full text Add to dashboard Cite

Almost 10% of the fish consumed in the world are produced by aquaculture. This regular supply of cultured fish is important to the food industry (Slinde, 1992). The aquaculture industry is expanding at a rapid pace. much of this growth coming from the increasing culture of salmonid species. Since its inception in the 1970s, the production of cultured salmon has grown to over 250 OW tons. The red colour, high quality, uniform size (approximately 4 kg) and year-round availability give cultured salmon its marketing appeal. Salmon represent a valuable source of 01-3 and w-6 fatty acids. which may prevent 'lifestyle diseases' (Skjervold. 1992), and increased consumption of fish is recommended. AQUACULTURE OF SALMONAs an anadromous species. Atlantic salmon (So/no salar) spends the juvenile part of its lifecycle in fresh water, migrates to the sea where the major growth phase occurs, and returns to spawn in the freshwater stream where it was born. Spawning occurs in the brisk currents of shallow cold waters. The female deposits eggs into an indentation in the river bed, and the male releases sperm over the eggs. In aquaculture. a broodstock is kept for production of eggs and sperm. A few months after fertilization. the fry hatches and 'start-feeding' commences (Figure I). The fingerlings grow until

show abstract

Somatostatin in the brain and the pituitary of some teleosts

Cited by 57 publications

References 24 publications

Long-Term Inhibitory Effects of Somatostatin and Insulin-Like Growth Factor 1 on Growth Hormone Release by Serum-Free Primary Culture of Pituitary Cells from European Eel (Anguilla anguilla)

Long-Term Inhibitory Effects of Somatostatin and Insulin-Like Growth Factor 1 on Growth Hormone Release by Serum-Free Primary Culture of Pituitary Cells from European Eel (Anguilla anguilla)

Distribution of somatostatin‐like immunoreactivity in the brain of the caecilian Dermophis mexicanus (amphibia: Gymnophiona): Comparative aspects in amphibians

Biotechnology in Aquaculture, with Special Reference to Transgenic Salmon

Contact Info

Product

Resources

About