Somatosensory temporal discrimination is impaired in fibromyalgia

Günendi, Zafer; Polat, Musa; Vurallı, Doğa; Çengiz, Bülent

doi:10.1016/j.jocn.2018.10.067

Cited by 13 publications

(20 citation statements)

References 29 publications

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“…In several studies conducted on healthy populations, the STDT value has been obtained as approximately 30 ms. [20][21][22] In a study which compared FMS patients with a healthy control group, the STDT value was mean 33 msn in the healthy control group and was significantly higher at mean 69 ms in the FMS patients. 6 The most likely reason for the high STDT values found in FMS patients is the impairment in the central processing process of painless tactile stimulation such as a pain stimulus. The basal ganglion, cerebellum, and primary somatosensorial cortex are thought to be the areas of the CNS responsible for the STD.…”

Section: Discussionmentioning

confidence: 99%

“…The procedures defined in previous studies were applied to measure STDT values. 4,6 The measurements were taken from the dorsum of the dominant hand of the fibromyalgia patients. First, the skin was cleaned with alcohol, then anodal and cathodal Ag-AgCl skin electrodes of 10 mm in diameter were placed at a distance of approximately 2-cm apart.…”

Section: Std Assessmentmentioning

confidence: 99%

“…These values have been found to be significantly higher in fibromyalgia, which is a central sensitization syndrome. 6 Therefore, the STD measurement can be used as a neurophysiological marker of the efficacy of fibromyalgia treatment.…”

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confidence: 99%

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The effect of supervised dynamic exercise program on somatosensory temporal discrimination in patients with fibromyalgia syndrome

et al. 2021

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Objectives: This study aims to investigate the effect of a supervised dynamic exercise program on somatosensory temporal discrimination (STD) which indicates the central sensory processing ability. Patients and methods: Forty-eight patients (mean age: 43 years; range, 19 to 64 years) with fibromyalgia syndrome (FMS) were included in this prospective, randomized study between April 2018 and October 2018. Demographics and clinical measurements were recorded. The STD threshold was measured by a researcher blinded to the treatment groups. After baseline assessments, the patients were randomized into two groups: the supervised exercise group (SEG) and the home exercise group (HEG) as the control group. The SEG performed submaximal aerobic exercise and low-medium resistant isotonic exercises under the supervision of a physiotherapist, 1-h per day, three days in a week for four weeks. The HEG was given a home-based exercise program consisting of low-to-medium resistance isotonic exercises and aerobic exercises 1-h per day, three days in a week for four weeks. After exercise program, clinical assessments and STD threshold measurement were repeated. Results: Clinical and STD threshold measures improved significantly after four-week exercise program in both groups. The improvements in clinical measures were significantly higher in the SEG. However, there was no difference in the STD threshold improvement between the groups. No correlation was found between the STD threshold measure and clinical features in any patients. Conclusion:Although a significant improvement was achieved in impaired STD threshold with SEG, it was not found to be superior to the amelioration observed with HEG.

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Section: Discussionmentioning

confidence: 99%

Section: Std Assessmentmentioning

confidence: 99%

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The effect of supervised dynamic exercise program on somatosensory temporal discrimination in patients with fibromyalgia syndrome

et al. 2021

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“…STD has been investigated in other disorders that show atypical sensory experiences and frontostriatal deficits. The results have shown that STDTs in Parkinson's disease, dystonia, multisystem atrophy, cerebellar atrophy, migraine, fibromyalgia, and multiple sclerosis were higher than in those of healthy controls [Abbruzzese & Berardelli, 2003; Artieda, Pastor, Lacruz, & Obeso, 1992; Boran, Cengiz, & Bolay, 2016; Conte et al, 2010; Gunendi, Polat, Vuralli, & Cengiz, 2019; Katschnig et al, 2010; Manganelli et al, 2013; Rocchi et al, 2013, 2016; Vuralli, Evren Boran, Cengiz, Coskun, & Bolay, 2016; Vuralli, Boran, Cengiz, Coskun, & Bolay, 2017]. It has been suggested that the cerebral cortex in individuals with ASD, including primary sensory areas, is affected by subtle changes in the neural circuits of perceptual processing [Robertson & Baron‐Cohen, 2017].…”

Section: Introductionmentioning

confidence: 99%

Somatosensory Temporal Discrimination in Autism Spectrum Disorder

et al. 2021

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Sensory differences are common in Autism Spectrum Disorder (ASD). While there is no well‐accepted method to measure sensory differences objectively, there is accumulating evidence from recent years concerning sensory perception, including data concerning temporal discrimination thresholds of individuals with ASD as measured by different measures. The somatosensory temporal discrimination (STD) test measures the threshold at which an individual can temporally discriminate multiple tactile stimuli delivered in succession. We aimed to investigate tactile perception in ASD and hypothesized that children with ASD have impaired STD related to their subjective sensory symptoms and daily difficulties. Thirty adolescents with ASD and 30 typically developed subjects were recruited. The Childhood Autism Rating Scale, Strengths and Difficulties Questionnaire, and Adolescent/Adult Sensory Profile were implemented before STD evaluation. Average somatosensory detection (1.48 ± 0.42) and discrimination thresholds (112.70 ± 43.45) of the children with ASD were significantly higher (P = 0.010, P = 0.001, respectively) than those of the controls (1.18 ± 0.42, 79.95 ± 31.60, respectively). Sensory seeking scores of the ASD group (40.8 ± 7.60) were significantly lower (P = 0.024) than those of the control group (45.83 ± 9.17). However, the psychophsycal thresholds did not have any statistically significant relationships with subjective sensory symptoms or daily difficulties. This study demonstrates impaired sensory processing in ASD evaluated by STD and its lack of relationship with subjective sensory symptoms and daily difficulties. This psychophysical evidence of increased STD thresholds and decreased sensory seeking profile supports the disturbances in the regulation of sensory processing in ASD. Lay Summary Sensory differences are common in autism; however, there is no well‐accepted method to measure them objectively. This study aims to investigate somatosensory differences and their relation with sensory and emotional/behavioral difficulties of children with autism. We show that autistic children have higher tactile discrimination thresholds and fewer sensory seeking behaviors. This supports the presence of impairments in sensory processing in autism. Measuring the sensory differences may help understanding clinical symptoms and neurobiological underpinings of autism. Autism Res 2021, 14: 656–667. © 2021 International Society for Autism Research and Wiley Periodicals LLC

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“…These two studies were of the case-control type, which is less evidenced and more liable to bias than randomized control trials. The first study has enrolled a larger number of patients than the second study, and both are of good quality after using the Newcastle-Ottawa quality assessment scale [6][7][8][9][10][11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%