Solvent selection for biphasic extraction of 5-hydroxymethylfurfural <i>via</i> multiscale modeling and experiments

Wang, Zhaoxing; Bhattacharyya, Souryadeep; Vlachos, Dionisios G.

doi:10.1039/d0gc03251d

Cited by 33 publications

(63 citation statements)

References 44 publications

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“…52 COSMO-RS has been recently applied in solvent screenings of biomolecules, e.g. for estimating the IL-solubilities of cellulose 53 , partition coefficients of 5-hydroxymethylfurfural in different biphasic solvent systems 54 , or extraction of lipids from yeast 55 . Furthermore, COSMO-RS was used to predict partition coefficients in biocatalytic biphasic systems 56 and was also applied for solvent screenings for lignin-based biorefineries 57,58 .…”

Section: Introductionmentioning

confidence: 99%

Computer-aided solvent screening for the fractionation of wet microalgae biomass

et al. 2021

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Section: Introductionmentioning

confidence: 99%

Computer-aided solvent screening for the fractionation of wet microalgae biomass

et al. 2021

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“…A common, and widely applied, strategy to improve the selectivity toward furfural and HMF is the use of water-immiscible organic solvents, such as toluene, methylisobutylketone, diethyl ether, ɣ-valerolactone (GVL) or p-xylene, to form an aqueous-organic biphasic system. 1,30,37,[54][55][56][57][58] Such aqueous-organic biphasic systems can be low-cost, relatively non-toxic and environmentally friendly. The concept of biphasic operation, based on the process of reactive extraction, exploits the continuous liquidliquid extraction of the newly formed HMF or furfural into the organic phase.…”

Section: Aqueous-organic Solvent Systemsmentioning

confidence: 99%

“…[59][60][61][62][63] The characteristics of these biphasic systems are variable in terms of catalysis and composition. 30,37,[54][55][56] While homogeneous catalysis from mineral acids remains the 14 preferred source, in several studies heterogeneous catalysis has also been successfully applied at biphasic conditions. 30,37 The effect of adding a water-immiscible layer affects the sugar-to-furan selectivity by continuous extraction of the newly formed HMF or furfural into the organic phase.…”

Section: Aqueous-organic Solvent Systemsmentioning

confidence: 99%

“…1,30,37,44,45 Biphasic operation has been applied to sugar dehydration at several aqueous-organic volume ratios, with mostly organic biphasic systems being reported to be the most beneficial in terms of sugar-to-furan selectivity. 1,20,37,[54][55][56] Large fractions of organic solvent, however, can be a limit for the efficiency of the process, as the feed for such a reaction comes as an aqueous solution and limiting the volume of the aqueous phase limits the final furan production. 1,57,58 The so-called 'solvent effect' resulting from adding such a co-solvent refers to changes in reaction rate, reaction pathway, product distribution, and yield.…”

Section: Aqueous-organic Solvent Systemsmentioning

confidence: 99%

“…124 Biphasic organic-aqueous operations are the state of the art for the production of furans at industrial scale, despite their limitations in sugar-to-furan selectivity. 1,30,37,[54][55][56][57][58] The application of polar organic solvents can cause logistic problems in industrial setups in which the starting material is wet biomass (Figure 2.3). Specifically, the major shortcoming of the application of polar organic solvents is the loss of solvent in the waste disposal step.…”

Section: Application Perspectivesmentioning

confidence: 99%

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Furfural manufacture from xylose : routes towards high selectivity and novel processes

Ricciardi

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Planet Earth is facing a human-induced climate crisis. 1 Scientists from numerous nations have raised concern about this issue at various instances in the past, with one of the latest public warning having arrived in January 2020. 1 The alarming trends observed in the parameters that we use to describe climate and environment (e.g., desertification, availability of fresh water, air pollution) show that drastic, politically driven changes are urgently necessary. 1 With greenhouse gas (GHG) emissions still rapidly rising, and most public discussions focused on global surface temperature only, it is of fundamental importance to understand that this environmental crisis is related to social and economic factors embedded in our society. 1,2 In parallel, and strongly related, to the climate crisis, our society is facing an energy crisis, which is directly connected to the steep rise in energy demand. 3,4 These two crises are intertwined, since the combustion of crude oil, natural gas and coal still is the primary energy sources worldwide, both for transportation of people and goods, fueling industry and infrastructures, and for ensuring the stability of the energy grid. 4 The product of combustion of these fossil fuels is CO2, which is an important contributor to the greenhouse effect. The increased energy demand is due to worldwide industrial development, coupled with an average increase of wealth. [3][4][5] This scenario, in combination with the increasing costs of extraction and manufacture of fossil fuels, is becoming a troubling bottleneck for economic development. [3][4][5] Currently, the addition of green and/or renewable sources of energy (e.g., hydroelectric, solar, wind and nuclear energy) is rapidly growing. 5 Yet, we must realize that just compensating the growing energy demand with these 'clean' energy sources is not sufficient. Reducing the (absolute) contributions of fossil fuels to the energy palette is absolutely necessary to act on the climate crisis and reduce, for example the CO2 levels in the atmosphere. 5 Making humanity fully independent from fossil fuels is an incredibly complex task. 1,2 To do so, the chain of production and consumption of energy, at all levels, needs to be redesigned with drastic, both politically and economically driven international choices. 1,2 Next to these necessary societal changes, research is needed to explore possible alternatives for fossil fuels, which would ease this transition with the aim to avoid, or minimize, an economic crisis. [1][2][3][4][5] Particularly, some sectors of industry and transportation, e.g., heavy industry and aviation, are extremely challenging to decarbonize and cannot solely rely on solar and wind energy, requiring the development of renewable fuels and chemicals. 6 Reducing, and finally eliminating, fossil resources such as oil is exceptionally complex, as these resources are also the basis for the current petrochemical industry. 6,7 The petrochemical industry, one of the largest during the last century, continues to grow t...

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Synthesis of mesoporous niobium phosphosilicate with high catalytic activity in the conversion of glucose to 5‐hydroxymethylfurfural in water solvent

Shen,

Zhu,

Cheng

et al. 2024

Biofuels Bioprod Bioref

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Mesoporous niobium‐based solid acid catalysts were successfully synthesized using the soft template method with sodium lignosulfonate (SLS) as the template. In most studies the template is calcined to form mesopores after hydrothermal synthesis; however, in this study SLS was retained to produce niobium‐carbon composite catalysts. The catalysts obtained were characterized by X‐ray diffraction, nitrogen adsorption–desorption, Fourier transform infrared spectroscopy, scanning electron microscopy, thermogravimetric analysis, and static contact angle measurements. The catalytic activity of the solids was also investigated in the conversion of glucose to 5‐hydroxymethylfurfural (HMF) using pure water as the solvent. Under optimal conditions, niobium‐carbon composite catalyst achieved a glucose conversion yield of 65.1% and an HMF yield of 42.1%. The enhanced catalytic activity was attributed to the timely extraction of the HMF by the carbonized SLS.

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Solvent selection for biphasic extraction of 5-hydroxymethylfurfural via multiscale modeling and experiments

Abstract: We report a comprehensive solvent selection framework where the COSMO-RS model is combined with high-throughput experiments at 298 and 423 K to formulate an extractant library for the reactive extraction of 5-hydroxymethylfurfural (HMF).

Cited by 33 publications

References 44 publications

Computer-aided solvent screening for the fractionation of wet microalgae biomass

Computer-aided solvent screening for the fractionation of wet microalgae biomass

Furfural manufacture from xylose : routes towards high selectivity and novel processes

Synthesis of mesoporous niobium phosphosilicate with high catalytic activity in the conversion of glucose to 5‐hydroxymethylfurfural in water solvent

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