Solvent selection and its effect on crystallization behavior of poly(ε-caprolactone) in electrospun poly(ε-caprolactone)/poly (lactic-co-glycolic acid) blend fibers

Super-Tough and Biodegradable Poly(lactide-co-glycolide) (PLGA) Transparent Thin Films Toughened by Star-Shaped PCL-b-PDLA Plasticizers

“…For that reason, PLGA has been extensively applied in various fields, including orthopedic fixation materials [ 11 , 12 ], guided bone regeneration (GBR) [ 13 , 14 ], artificial skin [ 15 , 16 ], wound dressing [ 17 , 18 ] and drug carriers [ 19 , 20 ]. An ideal material with high strength, stiffness, and toughness would be desirable for these applications [ 21 , 22 , 23 ]. However, the extensively application of PLGA has been hindered by its inherent brittleness and short degradation period, which cannot be applied as medical tissue materials.…”

“…To improve these drawbacks of biodegradable aliphatic polyesters, many strategies have been introduced via copolymerization [ 24 ], physical blending with plasticizers [ 11 ], composites [ 25 , 26 , 27 ], or rubbery elastomers [ 28 , 29 ], and addition of nanofillers [ 15 , 30 ]. Among these methods, the most commonly conducted method is combination of soft and ductile composite materials which include synthetic/natural materials [ 23 , 25 , 29 ] and organic/inorganic fillers or plasticizers [ 26 , 31 , 32 , 33 , 34 ]. This procedure is easy and simple.…”