Solutions for Care of Silicone Hydrogel Lenses

Willcox, Mark

doi:10.1097/icl.0b013e318275e0d9

Cited by 16 publications

(13 citation statements)

References 44 publications

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“…21 In addition, some mechanical complications have been linked to the higher modulus of SiHy lenses, 17,18,22,23 although the prevalence of these complications appears to be reduced with more recently introduced SiHy materials. 25,26 However, the combination of certain lens materials with some multipurpose disinfecting solutions may result in solution-induced corneal staining (SICS) with an increased prevalence of corneal infiltrates, 19,27 and at higher levels, SICS may necessitate a temporary cessation of lens wear. The multipurpose soft lens disinfecting solutions are able to simultaneously disinfect, clean, reduce deposition, and improve comfort with wetting agents.…”

mentioning

confidence: 99%

Clinical Performance of Three Silicone Hydrogel Daily Disposable Lenses

Varikooty

Schulze²,

Dumbleton³

et al. 2015

Optometry and Vision Science

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Each of the three SiHy DDCLs performed well. Noninvasive tear breakup time was longest and wettability was greater with DT1. C1D had the most conjunctival staining conjunctival indentation. There was no difference between asymptomatic and symptomatic wearers with regard to ocular response and contact lens-related parameters. These results suggest that SiHy DDCLs may be an excellent contact lens modality for the symptomatic patient.

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mentioning

confidence: 99%

Clinical Performance of Three Silicone Hydrogel Daily Disposable Lenses

Varikooty

Schulze²,

Dumbleton³

et al. 2015

Optometry and Vision Science

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“…Multipurpose contact lens solutions are dual-purpose liquids that both clean and disinfect contact lenses. Multipurpose solutions were previously marketed as "no-rub" solutions, because they are designed to adequately clean and disinfect lenses with a simple rinse-and-store method, eliminating the need to mechanically rub the lenses to remove lens deposits [9]. In recent years there has been a global recall of at least one brand of a multipurpose contact lens solution because of an outbreak of eye infections associated with the product [10].…”

Section: Introductionmentioning

confidence: 99%

The In Vitro Anti-Microbial Activity of Multipurpose Contact Lens Solutions against Standard Strains of Common Ocular Pathogens: The Effect of Duration from First Use

Iguban¹,

Nanagas²

2016

J Clin Exp Ophthalmol

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Objective: This study aims to determine the in vitro anti-microbial efficacy of opened multi-purpose contact lens solutions on common contact lens-related ocular pathogens. Specifically, this study intend to compare the log reduction in microbial concentration when exposed to newly opened, 5 months-opened, and 10 months-opened multi-purpose contact lens solutions.Methods: This is a single-blind controlled experiment that evaluated five locally available multi-purpose contact lens solutions (MPS) in terms of their antimicrobial efficacy towards common contact lens-related ocular pathogens using the stand alone criteria. Newly opened, 5-month old, and 10 -month old multipurpose contact lens solutions were compared based on their effect in reducing microbial concentration at 6 hours of exposure.Results: Multi-purpose contact lens solutions (MPS) containing polyquaternium-1 and myristamidopropyl dimethylamine (MAPD) as well as polyhexamide reduced the bacterial concentrations by 3 log and fungal concentrations by 1 log, enabling them to fulfill the stand alone criteria for disinfecting solutions. This antimicrobial efficacy was most evident with newly-opened contact lens solutions, followed by those opened for five months. Those which were opened for 10 months showed limited anti-microbial activity for both bacteria and fungi. Conclusion:Multipurpose contact lens solutions demonstrated variability in their antimicrobial activity, which are significantly affected by the kind of MPS used and the duration from the date of first use. Multi-purpose contact lens solutions (MPS) containing polyquaternum and MAPD are preferred due to its broad spectrum efficacy and effectivity. They must be utilized before their expiration date since results have shown a decrease in anti-microbial activity with an increase in duration from first use. This is to prevent contact-lens related ocular infections brought about by exposure to humid climate.

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“…26 The use of external wetting agents, such as surfactants, was initially used to help the removal of lipid deposits, but it has also been added to lower the surface tension of the solution, providing increased viscosity and enhanced wettability. These agents include propylene glycol, hyaluronan, hydroxypropyl methylcellulose, and polyquaternium 10 (quaternized hydroxyethyl cellulose).…”

mentioning

confidence: 99%

“…These agents include propylene glycol, hyaluronan, hydroxypropyl methylcellulose, and polyquaternium 10 (quaternized hydroxyethyl cellulose). 26 To improve initial lens comfort and wettability, a number of manufacturers have also included a variety of wetting agents and surfactants into packaging or blister solutions. 27,28 Corneal staining and clinical performance with MPDS have been well covered in the literature; however, there continues to exist areas in which these products are not fully understood as the interaction between lens polymers and chemical composition of MPDS.…”

mentioning

confidence: 99%