Effect of Lens Care Systems on Silicone Hydrogel Contact Lens Hydrophobicity

Lira, Madalena; Silva, Rita

doi:10.1097/icl.0000000000000247

Cited by 19 publications

(16 citation statements)

References 34 publications

(42 reference statements)

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“…It should be noticed that both in our control experiments (data not shown) and in publications by independent teams TE and AOD type of materials were found to display advancing contact angles ≥47° even in absence of desiccation stress and with all the wetting agents being present (i.e., with the CLs freshly removed from blisters and without exposure to air) [7,21,22,28,29]. Considering that it has been claimed [30] that the internal wetting agents infused in the core of senofilcon A and narafilcon A are not blink released (i.e., significantly resisting a depletion by the aqueous tear turnover) it is further indication on the importance of true surface coatings/treatments for the low water CA of CL.…”

Section: Discussionmentioning

confidence: 64%

“…of the CL performance [1,14,28]. The data on the impact of internal wetting agents on the contact angles of worn SiHy CLs are also inconclusive [7,8] and although it was found that the presence of PVP (wetting agent) does not significantly improve the clinical performance of SiHy [31], the small sample size (40 patients per CL sample) limited the statistical power of the study.…”

Section: Discussionmentioning

confidence: 99%

“…Great efforts have been devoted to the design of daily disposable SiHy CLs that can maintain high wettability even after extended wear. Different approaches have been implemented [7,8]: (i) from incorporation of wetting agents (polyvinylpyrrolidone, poloxamers, etc.) in the CL core and in CL solutions to (ii) the design of sophisticated CL surfaces with high water holding properties.…”

Section: Introductionmentioning

confidence: 99%

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Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels

Eftimov

Yokoi

Peev

et al. 2019

IJMS

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The wettability of silicone hydrogel (SiHy) contact lens (CLs) is crucial for the pre-lens tear film stability throughout the day. Therefore, sessile drop and captive bubble setups were used to study the advancing and receding water contact angles (CA) of four SiHy materials: narafilcon A (TE), senofilcon A (AOD), stenfilcon A (MD), and delefilcon A (DT). TE and AOD have 48% and 38% water content, respectively, and no surface coating. MD (54% water) implements “smart chemistry” with just 4.4% bulk silicone content, while DT has >80% water at its surface. These SiHy were subjected to continuous blink-like air exposure (10 s)/rehydration (1s) cycles for 0, 1, 2, 3, 4, 6, 8, 10, 12, 14, and 16 h. The advancing CA, which measures the rehydration propensity of the CL surface, proved to be the most sensitive parameter to discriminate between the samples. The order of performance for the entire time scale was DT > MD >> AOD ≥ TE. The extended desiccation/rehydration cycling increased the differences between the CA of DT and MD compared to AOD and TE. This suggests that the low Si surface content and the high surface hydration are major determinants of SiHy wettability.

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Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels

Eftimov

Yokoi

Peev

et al. 2019

IJMS

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“…Alcon proposed to exploit this phenomenon in OPTI‐FREE Puremoist to enhance the wettability of silicone hydrogel contact lens surfaces (Campbell et al, ). Indeed, Lira and Silva evaluated the change in the wettability of five lens models after incubation with four MPSs and reported lower water contact angles on four of the five lenses tested after incubation with OPTI‐FREE Puremoist relative to their respective angles measured just out of the packing solution,(Lira & Silva, ) which was also true with ReNu MultiPlus MPS (Bausch and Lomb) containing Tetronic 1107 surfactant.…”

Section: Discussionmentioning

confidence: 92%

Effect of multipurpose care solutions upon physical dimensions of silicone hydrogel contact lenses

et al. 2019

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Interactions between contact lens multipurpose solution (MPS) components and the contact lenses with which they are used are both lens and solution dependent. As such, lens dimensional changes may arise after cleaning and immersion cycling in different lens care solutions over different time courses. In this study, the dimensional stability of five planned-replacement silicone hydrogel lenses (lotrafilcon B, comfilcon A, senofilcon A, senofilcon C, and samfilcon A) over 30 cycles in three different MPSs (Biotrue, OPTI-FREE Express, and OPTI-FREE Puremoist) was evaluated. Measurements of diameter, sagittal depth, power, roundness, and center thickness were obtained prior to, during, and after 30 cycles of cleaning and storage. Diameters of all lenses increased when soaked in Express or Biotrue but held the International Standards Organization (ISO) tolerance over the full course of 30 disinfection cycles; however, the diameters of comfilcon A, senofilcon A, senofilcon C, and samfilcon A lenses soaked in Puremoist exceeded ISO tolerance after between 4 and 9 immersion cycles. In contrast, the diameter of lotrafilcon B held tolerance. Similarly, all lenses cycled in Express or Biotrue held tolerance for sagittal depth, while in Puremoist only lotrafilcon B held tolerance. All lenses became less round in all MPSs but held tolerance for both power and central thickness. Given the lack of reported clinical issues with Puremoist when used with lenses other than lotrafilcon B, we propose that it may be appropriate to revisit the ISO test methods and tolerances to determine if they are still applicable for silicone hydrogel lenses. K E Y W O R D S ISO, lens care, lens-solution compatibility, multipurpose solution (MPS)

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“…Tear film dysfunction causes pain and enhanced immune activity, which may interfere with vision [18]. Some studies have shown that the coefficient of friction (COF) of silicone hydrogels may be changed due to long-term reaction with the tear film components, indicating that long-lasting moist lens is favourable for maintaining a low COF in a long time [19], and some research studies related to the design of novel highly weTable contact lens materials have been done already [20][21][22]. Blinking and eye rotation are the most important physiological processes for lens and lens friction, which can lead to various corneal infections, corneal ulcers, decreased vision, and other symptoms [23].…”

Section: Introductionmentioning

confidence: 99%

Tribological behaviour of two kinds of typical hydrogel contact lenses in different lubricants

Qin

Zhu

Zhou

et al. 2019

Biosurface and Biotribology

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Contact lenses have a special effect on the treatment of some eye diseases. The tribological behaviour of soft contact lenses considerably influences their clinical performance. Improper wearing of contact lenses can lead to mechanical damage of the contact interface, which can lead to pathological changes in the eyeball. In this study, the sliding friction of two kinds of typical contact lens materials (hilaficon-B and lotrafilcon-B) in three lubricants (distilled water, care solution, and eye drop) and tribological parameters are studied, using PMMA as a control. Hydrogels have high water content but the dehydration rate is high. Silicone hydrogels have low initial water content but low dehydration rates. The friction test in distilled water gives the highest coefficient of friction value. The care solution and eye drop significantly reduce the friction coefficient of the lens due to the formation of tribofilm.

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Effect of Lens Care Systems on Silicone Hydrogel Contact Lens Hydrophobicity

Cited by 19 publications

References 34 publications

Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels

Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels

Effect of multipurpose care solutions upon physical dimensions of silicone hydrogel contact lenses

Tribological behaviour of two kinds of typical hydrogel contact lenses in different lubricants

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