Solution thermodynamics and preferential solvation of 3-chloro-N-phenyl-phthalimide in acetone + methanol mixtures

Abstract

The thermodynamic properties of the 3-chloro-N-phenyl-phthalimide in acetone+ methanol cosolvent mixtures were obtained from solubility data report in literature. The solubility was higher in near acetone and lower in pure methanol at all temperatures studied. A non-linear plot of ∆ from pure acetone up to x 1 soln H° vs. ∆ soln 2, Gerson G° shows a negative slope = 0.691. Beyond this composition, a variable positive slope is obtained with the exception of mixtures with x 1 = 0.121, x1 = 0.272 and x 1= 0.356 which is a not common trend in these systems. The preferential solvation of 3-chloro-N-phenyl-phthalimide by the components of the solvents was estimated by means of the inverse Kirkwood–Buff integral method, showing the 3-chloro-Nphenyl-phthalimide is preferential solvated bymethanol in more polar mixtures and by acetone in less polar ones.

Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures

“…Once D and Q are calculated together with the isothermal compressibility (κT) for water (0.457 GPa −1 ) [68] and ethanol (1.248 GPa −1 ), in addition to the molar volumes of amygdalin and the solvents in the binary mixture reported by Jiménez et al [69], the Kirkwood-Buff integrals are calculated, and from these, the preferential solvation parameters δx1.3 of amygdalin in the binary solvent mixtures at the studied temperatures are calculated [70]. On the other hand, Q is calculated according to Equation (19), where G 1.2 E is calculated as [64]:…”

“…calculated, and from these, the preferential solvation parameters δx 1,3 of amygdalin in the binary solvent mixtures at the studied temperatures are calculated [70].…”