Soluble tumor necrosis factor-α receptor type 1 during selenium supplementation in psoriasis patients

Serwin, Agnieszka Beata; Myśliwiec, Hanna; Hukalowicz, K.; Porebski, Piotr; Borawska, Maria H.; Chodynicka, B

doi:10.1016/s0899-9007(03)00165-5

Cited by 19 publications

(12 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Selenium deficiency is reported to be one of the risk factors which could lead to susceptibility to inflammatory skin diseases [ 31 – 33 ]. An ample amount of studies are available showing low serum Se concentration in psoriasis patients [ 6 , 34 , 35 ]. Kadry et al have found that plasma Se levels were lower, osteopontin levels were extremely higher in the patient group compared to the control group and proposed that over-expression of osteopontin and low Se levels could be associated with the pathogenesis of psoriasis [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

Trace elements and oxidative stress status in patients with psoriasis

Kirmit

Kader

Aksoy

et al. 2020

pdia

View full text Add to dashboard Cite

Introduction: Psoriasis is a common, inflammatory skin disease of which etiopathogenesis is still not explained clearly, however in which trace elements and oxidative stress are considered to play a role. Aim: To evaluate the serum trace element and oxidative stress levels in patients diagnosed with psoriasis. Material and methods: A total of 87 psoriasis patients and 60 healthy subjects were included in the study. Serum sodium (Na), potassium (K), calcium (Ca), phosphorus (P), magnesium (Mg), iron (Fe), selenium (Se), zinc (Zn), copper (Cu) levels, oxidative stress parameters, ischemia-modified albumin (IMA), catalase (CAT), myeloperoxidase (MPO) and ferroxidase (FOX) activity and an inflammatory marker, C-reactive protein (CRP), were examined in all participants. Results: IMA, IMA/Albumin (IMA/Alb), CAT, Cu, FOX and CRP levels were found to be significantly higher; Se, Zn and albumin levels were significantly lower in the patient group as compared to the control group. No significant difference was found between groups with regard to Na, K, Ca, P, Mg, Fe and MPO levels. Conclusions: Some trace element levels and oxidant-antioxidant balance were changed in psoriasis patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Trace elements and oxidative stress status in patients with psoriasis

Kirmit

Kader

Aksoy

et al. 2020

pdia

View full text Add to dashboard Cite

show abstract

“…In another case-control study by Serwin et al, 22 patients received topical 5% salicylic acid ointment, 0.1% to 0.3% dithranol ointment, and 200 μg daily selenomethionine versus placebo for 4 weeks 38 . Both groups achieved almost complete remission, but the PASI score was higher in the selenium group (p < 0.05) and the TNF level was also higher in the selenium group.…”

Section: Resultsmentioning

confidence: 99%

Diet and psoriasis, part III: Role of nutritional supplements

Millsop

Bhatia

Debbaneh

et al. 2014

Journal of the American Academy of Dermatology

View full text Add to dashboard Cite

Psoriasis patients are increasingly turning to the use of alternative and complementary medicine to manage their psoriasis. Patients often inquire about what dietary supplements may be beneficial, including the use of oral vitamin D, vitamin B12, selenium, and omega-3 fatty acids in fish oils. In this review we examine the extent to which each of these common nutritional interventions has been studied for the treatment of psoriasis. We weighed evidence from both controlled and uncontrolled prospective trials. The evidence of benefit was highest for fish oils. For other supplements, there is need for additional large, randomized clinical trials to establish evidence of efficacy.

show abstract

“…At the end of the trial, PASI scores decreased from 14.68 ± 7.97 to 4.30 ± 3.92 and from 11.85 ± 6.73 to 1.67 ± 1.17 (P < 0.05) in those receiving selenomethionine and placebo, respectively. 25 In another study by Serwin et al, patients with plaque psoriasis receiving narrowband ultraviolet B (NB-UVB) therapy and either 200 μg selenomethionine or placebo showed similar reductions in mean PASI scores. 26 Harvima et al also found that selenium supplementation is not effective in treating psoriasis.…”

Section: Seleniummentioning

confidence: 99%

Alternative Medicine for the Treatment of Psoriasis

2013

View full text Add to dashboard Cite

The use of complementary and alternative medicine has an estimated prevalence of about 51% amongst patients with psoriasis. The relatively lower costs, perceived fewer side effects, and versatile use alone or in combination with standard psoriasis treatments have increased its appeal. Clinical trials and case reports have investigated the use of dietary supplements, herbs, gluten-free diet, acupuncture, psychotherapy, meditation, and hypnosis for the treatment of psoriasis. Fish oil, vitamin D, inositol, curcumin, indigo naturalis, Aloe vera, capsaicin, and Mahonia aquifolium have shown some efficacy in some of the clinical trials covered in this review. Gluten-free diets and the use of meditation and stress-reduction exercises also have shown to help improve the clinical symptoms of psoriasis. Knowledge of these treatments can help dermatologists educate their patients who are interested in alternative remedies for psoriasis.

show abstract

Soluble tumor necrosis factor-α receptor type 1 during selenium supplementation in psoriasis patients

Cited by 19 publications

References 20 publications

Trace elements and oxidative stress status in patients with psoriasis

Trace elements and oxidative stress status in patients with psoriasis

Diet and psoriasis, part III: Role of nutritional supplements

Alternative Medicine for the Treatment of Psoriasis

Contact Info

Product

Resources

About