Solitary neurofibroma of the nasal cavity: resection with endoscopic surgery

Abstract

We present a case of neurofibroma of the nasal cavity treated by endoscopic surgery. A 71-year-old female had complained of left-sided nasal obstruction for the past four years. Anterior rhinoscopy, computed tomography (CT) and magnetic resonance imaging (MRI) revealed a tumour involving the left nasal cavity. Histological and immunohistochemical examination showed the tumour to be a neurofibroma. The tumour was resected with endoscopic surgery. Neurofibroma arising in the area of the nose and paranasal sinuses is rare. We discuss the clinical and pathological characters of neurofibroma arising in the nasal cavity.

Solitary nasal neurofibroma presenting as compressive optic neuropathy

“…2 Neurofibroma in the nasal cavity often leads to nonspecific symptoms including nasal obstruction, cheek swelling, and epitaxis. 3,4 The tumour can also erode into the orbit 5 but to our knowledge there has not been any case reports in which the patient presents with compressive optic neuropathy as in this case. Radiologically, the tumour may resemble a malignant tumour because of the presence of bony destruction.…”

A Case of Solitary Neurofibroma in Outer Surface of Nose

“…Considering ultrastructural features, this is composed of a mixture of perineural fibroblasts and Schwann cells, which are S-100 positive. 7,14 CT scanning and MRI are the main imaging methods used to reveal the size of the tumor, which is essential to plan further interventions such as surgical excision. Mostly MRI is thought to outweigh CT images since it can allow better distinction of the tumor from neighboring soft tissues, beside enhanced assessment of possible intraorbital and intracranial extension.…”

“…Mostly MRI is thought to outweigh CT images since it can allow better distinction of the tumor from neighboring soft tissues, beside enhanced assessment of possible intraorbital and intracranial extension. 12,14 The general management of neurofibromas mostly depends on the signs and symptoms which patient presents with. Small lesions not causing any issues may not require any invasive interventions, other than monitoring.…”

Endoscopic Excision of Solitary Neurofibroma Arising from Posterior Nasal Septum

“…In most papers, only one or two cases are described. [5][6][7][8] Signs and symptoms depend on the anatomic site involved, the nerve of origin and the extent of the tumor. Patients may complain of unilateral nasal obstruction, epistaxis, mucopurulent rhinorrhea, anosmia, facial swelling, proptosis and pain when the maxillary sinus AIJCR These lesions may be well circumscribed or may blend into surrounding connective tissue.…”