Solitary metastasis to the penis from prostate adenocarcinoma - a case report

Abstract

Penile metastasis from prostate adenocarcinoma is rare and the disease is usually disseminated at presentation. We present a case of an 83-year-old man with solitary metastasis to the penis from prostate adenocarcinoma. The clinical presentation and imaging features of penile metastasis from prostate cancer and the other primary penile tumors are discussed.

Patient with penile metastasis from prostate cancer and survival over 5 years: A case report with longitudinal evaluation using computed tomography and magnetic resonance imaging

“…The median age reported for penile metastases from prostate cancer ranged from 65 to 75 years [7] . As in the present case, most patients have bony metastases when they present with penile metastases [4] . The most common clinical signs are penile pain, ulceration, painful or painless palpable penile nodules, priapism, urinary retention, dysuria, and hematuria [4 , 8] .…”

“…As in the present case, most patients have bony metastases when they present with penile metastases [4] . The most common clinical signs are penile pain, ulceration, painful or painless palpable penile nodules, priapism, urinary retention, dysuria, and hematuria [4 , 8] . The most accepted mechanisms of penile metastasis include arterial, venous, lymphatic metastasis, and direct invasion as other secondary malignancies.…”

“…The treatment of penile metastasis should be aimed at palliation and improving the quality of life. The treatment options include local excision of the tumor, radiation therapy, bilateral orchiectomy, additional hormonal and chemotherapy, and partial or total amputation of the penis [1 , 4 , 8 , 11] . In the present case, the patient received palliative radiation (8 Gy/1 fr) for the penile metastasis, which induced remission of pain.…”

“…Penile metastasis of malignant tumors is a rare condition with poor prognosis, with a mean survival time of 9 months [1] and the longest reported survival time of 30 months [2] . Although some authors have described magnetic resonance imaging (MRI) findings of penile metastasis [3 , 4] , there have been no reports on longitudinal MRI examinations. We report a case of a patient with penile metastasis of prostate cancer, with survival of more than 5 years after the initial diagnosis and a review the MRI findings.…”

Erythematous papules on the penis as first manifestation of metastatic prostate adenocarcinoma

“…Penile sarcoma represents less than 5% of penile tumors and manifests as an indurated mass without any specific location. B-cell lymphoma of the penis can manifest as a nodule, indurated plaque, diffuse penile swelling, or a non-healing ulcer that involves the shaft or the glans associated with a peri-urethral abscess [4,5]. Penile involvement in prostate cancer is associated with a poor prognosis, with a four to 18month period since the development of the metastatic lesions to death [3].…”