Patient with penile metastasis from prostate cancer and survival over 5 years: A case report with longitudinal evaluation using computed tomography and magnetic resonance imaging

Abstract

Penile metastasis of malignant tumors is a very rare condition, often occurring as a part of systemic metastases, and is therefore associated with a poor prognosis. Although there have been reports of magnetic resonance imaging findings of penile metastasis, longitudinal imaging changes have not been presented previously. We report a case of a 80-year-old male patient with penile metastasis from prostate adenocarcinoma. First magnetic resonance imaging demonstrated multiple penile nodules in the left corpus cavernosum corpora cavernosa, and these nodules were fused and across the septum of the penis, forming an enlarged, diffusely spreading mass on the follow-up exam 5 years later. In this case, a longitudinal evaluation of magnetic resonance imaging demonstrated the course of the extension of the rare penile metastasis.

Unusual Presentation of Solitary Penile Metastasis of Prostate Cancer on 68Ga-PSMA PET/CT

“…[1][2][3] Few case reports presented penile metastasis postradical prostatectomy, which are however often associated with more disseminated systemic disease. [4][5][6][7] To our knowledge, this is the first case presented with solitary penile metastases diagnosed 3 years postradical resection of the primary tumor and adjuvant pelvic radiotherapy. Penile metastases depict negative prognosis, with limited median survival.…”

Isolated, PSMA-negative penile metastasis from castration resistant prostate adenocarcinoma, identified by FDG-PET

“…Patients present with palpable nodules, penile pain, dysuria, priapism, urinary voiding issues and ulcerations. Average survival rates for penile metastases from the prostate is 9 months with the longest documented being 5 years, described by Fujita et al 3 Patients with penile metastasis from urological source, presenting with priapism have been known to demonstrate worse survival rates when compared to those without priapism.…”

Malignant refractory priapism in case of urothelial cancer. Case report

“…Среди методов медицинской визуализации метастатического поражения полового члена используют ультразвуковое исследование с допплерографией, МРТ [12,22,23]. По мнению авторов, каждый способ имеет свои преимущества и ограничения, тем самым не может дать однозначного ответа в сложных клинических случаях [15].…”