Solitary intracerebral schwannoma in von recklinghausen's disease

Bruni, P; Esposito, Stefano; Greco, Romano; Oddi, G

doi:10.1016/0090-3019(84)90140-x

Cited by 41 publications

(21 citation statements)

References 11 publications

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“…[5][6][7]9,25,43,[45][46][47]50 Although schwannomas tend to occur in individuals with NF2 and schwannomatosis, studies have documented an association of intracerebral schwannomas with NF1. 8,13,16,33,35 Most reported cases have been seen in children or young adults. 1,16,21,22,24,48,50 Cases occurring in adults beyond the 3rd decade of life have been reported.…”

Section: Discussionmentioning

confidence: 99%

“…Schwann cell proliferation has been observed in patients following stroke or in individuals with diabetes mellitus. 8,34,40 On imaging, intracerebral schwannomas have been shown to display calcifications, cysts, and peritumoral edema. 19,30,31,50,57 Noncystic tumors have also been reported, most commonly in the frontal lobes.…”

Section: Discussionmentioning

confidence: 99%

“…8,27 The presence of intracerebral schwannomas within the brain parenchyma is rare. They remain an elusive entity, with only a few case reports and small series available for review.…”

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confidence: 99%

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Intracerebral schwannomas: a rare disease with varying natural history

Scott

Koral²,

Margraf

et al. 2013

PED

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Although intracerebral schwannomas are typically regarded as benign intracranial tumors, malignancy and recurrence have been reported among patients harboring such neoplasms. The available literature consists of case reports and small series that present variable characteristics distinguishing these unusual lesions. Little advancement has been made to further the understanding and management of these tumors. The authors present 3 cases from their institution that highlight the difference between typical benign intracerebral schwannomas and histopathological variants that may portend more aggressive behavior. Also provided is a review of the literature in the hope of gaining a better understanding of these rare tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Intracerebral schwannomas: a rare disease with varying natural history

Scott

Koral²,

Margraf

et al. 2013

PED

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“…A associação destes tumores intraaxiais com neurofibromatose não é comum, tendo sido descrito apenas um caso na literatura (Bruni e col. 26 ). Sua apresentação como lesão tumoral de caráter maligno é incomun, também com descrição de apenas um caso na literatura (Stefanko e col. 27 ).…”

Section: Discussionunclassified

Schwanoma intracerebral talâmico: relato de caso

Andrade

Neto

Braga

2002

Arq. Neuro-Psiquiatr.

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RESUMO -Os schwanomas intracranianos compreendem cerca de 8% de todos os tumores cerebrais porém, aqueles classificados como intra-axiais são mais raros, havendo somente 55 casos relatados na literatura. O diagnóstico é feito pelo tipo e arranjo celular comum aos tumores de bainha nervosa, pela imuno-histoquímica (GFAP, proteína S-100, EMA) e pela microscopia eletrônica. Sua apresentação clínica é variável, dependendo de sua localização; suas características neurorradiológicas não se apresentam de maneira típica. O tratamento cirúrgico, com exérese total da lesão, propicia a cura. Possuem caracteres benignos; um dos casos relatados na literatura, possuía entretanto caracteres de malignidade. Apresentamos um caso de schwanoma cerebral intra-axial supratentorial localizado na região talâmica esquerda, com confirmação diagnóstica anatomopatológica e imuno-histoquímica. Em tal localização não fora encontrado nenhum caso na literatura. PALAVRAS-CHAVE: schwanoma intracerebral, talâmo. Thalamic intracerebral schwannoma: case reportABSTRACT -The intracranial schwannomas cover about 8% of all the brain tumors, although, those localized inside the encephalic parenchyma are rare only 55 cases being reported in the literature. The histhopatologic diagnosis is based on the cellular type and arrangement common to the nervous sheat tumors, the immunohistochemical findings (GFAP, S-100 protein, EMA) and electronmicroscopic findings as well. The clinical presentation related to the intraparenchimatous schwannoma is variable, depending on its localization, the image diagnosis does not show any typical aspect. The surgical treatment is curative once a complete extirpation is obtained. These tumors are benign but one case reported presented malignant signs. We present a patient that had a thalamic schwannoma with histological confirmation. We found no case with this localization in the literature. Schwanomas são tumores benignos que se originam das raízes de nervos cranianos ou espinhais. Correspondem a cerca de 8% de todos os tumores intracranianos 1 . Apesar de raros, estes tumores já foram relatados ocorrendo em todos os nervos cranianos. Por definição, a diferença entre schwanoma, neurofibroma e neurilemoma baseia-se na localização destas lesões, pois todas se originam das células de Schwann, sendo o schwanoma natural dos nervos intracranianos e intrarraquianos. O neurofibroma apresenta-se associado a lesões cutâneas e subcutâneas, presentes na neurofibromatose do tipo I e II o neurilemoma localiza-se ao longo de fibras nervosas periféricas, particularmente nos plexos cervical, braquial ou lombossacro. Sua localização intraparenquimatosa encefálica é rara. Foram descritos 55 casos (Tabela 1), sendo 36 supratentoriais (Tabela 2) e 19 infratentoriais (Tabela 3), dos quais 13 localizados no cerebelo e vermis cerebelar, 2 na ponte, 1 no bulbo e 3 no tronco cerebral. Foram ainda descritos 44 casos intramedulares 2 . Relatamos o caso de um paciente jovem que apresentava quadro evolutivo de hipertensão intracraniana, com hidrocefalia ...

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“…1,3-6,8-11, 13,17,18,21,22) Various intracranial schwannomas unrelated to cranial nerves have all been adherent to the dura mater. 1,[3][4][5][6][7][8][9][10][11]13,17,18,21,22) Therefore, these tumors are thought to arise from the dura mater.…”

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confidence: 99%

Dura-Based Giant Intracranial Schwannoma in the Middle Fossa -Case Report-

Inui

Morimoto

Koshimae

et al. 2007

Neurol. Med. Chir.(Tokyo)

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A 49-year-old female presented with a rare giant schwannoma arising from the dura mater of the middle fossa manifesting as loss of left visual acuity. Magnetic resonance imaging revealed a heterogeneously enhanced giant mass in the left middle fossa. Surgery via the transsylvian approach confirmed the origin of the tumor between the left internal carotid artery and the trigeminal nerve in the lateral wall of the cavernous sinus. Elongated abducens nerve was confirmed, but no tumor adhesion to the abducens nerve was found. The tumor was closely attached to the dura mater of the middle fossa and the lateral wall of the cavernous sinus. The histological diagnosis was schwannoma. Both left oculomotor and abducens nerve pareses occurred immediately after the operation but gradually resolved over 3 months. The operative findings indicated that this schwannoma may have arisen from the meningeal branch of the trigeminal nerve in the dura mater of the middle fossa.

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Solitary intracerebral schwannoma in von recklinghausen's disease

Cited by 41 publications

References 11 publications

Intracerebral schwannomas: a rare disease with varying natural history

Intracerebral schwannomas: a rare disease with varying natural history

Schwanoma intracerebral talâmico: relato de caso

Dura-Based Giant Intracranial Schwannoma in the Middle Fossa -Case Report-

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