Solitary Extramedullary Plasmacytoma in the Oropharynx: Advantages of Intensity-Modulated Radiation Therapy

Solitary extramedullary plasmacytoma of the parotid gland in a patient with mixed connective tissue disease

“…There are even suggestions for higher dosages for better local control of the disease and higher survival rates. [ 10 ] Radiotherapy after excision of the SEP in the parotid gland is not standard practice, yet, some authors recommend it to prevent local relapse. From the published cases in the literature, almost half of the cases with SEP in the parotid gland received radiotherapy after excision, and 3 of them received only radiotherapy without surgery first.…”

Managing xerostomia

“…Systemic drugs like Pilocarpine and Cevimeline 15 slow the loss of functional salivary gland tissue, as does Amifostine, 16 a chemoprotective drug that prevents salivary gland damage from chemotherapy or radiation therapy for cancer. Targeted 17 or Intensity Modulated Radiation Therapy 18 also minimises radiation exposure and damage of the salivary glands.…”