Solitary Chest Wall Tuberculosis Mimicking a Malignancy Demonstrated on FDG PET/CT

Liu, Xiao; Li, Yuhao; Li, Lin

doi:10.1097/rlu.0000000000004219

Cited by 2 publications

(3 citation statements)

References 16 publications

(25 reference statements)

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“…[ 18 F]FDG PET/CT also allowed us to exclude relapse in cases of postoperative fibrosis in patients with abnormal CT results, and this observation is similar to the one made in previous reports [11,18]. When describing the role of [ 18 F]FDG PET/CT imaging in the diag nosis of patients suspected of relapse it should be mentioned that this whole-body examination enables to detect not only distant metastases but also other synchronous conditions [37][38][39][40][41]. It was confirmed in our study.…”

Section: Originalsupporting

confidence: 79%

The value of [18F]FDG PET/CT examination in the detection and differentiation of recurrent ovarian cancer

Kosinska,

Misiewicz,

Kalita

et al. 2023

Nucl. Med. Rev.

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Background:The exact role of positron emission tomography with fluorine-18-deoxyglucose ([ 18 F]FDG PET/CT) in an early diagnosis of relapsed ovarian cancer is not clearly defined. The aim of the study was to assess the value of [ 18 F]FDG PET/CT in the detection and differentiation of recurrent ovarian cancer.Material and methods: Eighty-four patients with suspected recurrent ovarian cancer underwent [ 18 F]FDG PET/CT examination. Results of PET/CT were analyzed taking into account clinical data of the patients, histological diagnosis, and 6-month follow-up. Results:The [ 18 F]FDG PET/CT examinations showed abnormal findings in 67 patients (79.76%). There were 63 true positive results (75.00%), 14 true negative (16.67%), 4 false positive (4.76%), and 3 false negative (3.57%) results. Sensitivity, specificity, positive and negative predictive values of [ 18 F]FDG PET/CT were 95%, 78%, 94%, and 82%, respectively. In patients with elevated serum Ca 125 concentration (n = 43), sensitivity and specificity of [ 18 F]FDG PET/CT was 95.00% and 66.67%, respectively. Recurrence was confirmed in 22 (88.00%) of 25 patients referred for [ 18 F]FDG PET/CT due to suspected relapse in imaging tests. Conclusions:A high frequency of recurrent ovarian cancer detected in the [ 18 F]FDG PET/CT examinations due to increased Ca 125 concentration in patients without clinical symptoms and without changes in other imaging tests confirmed the usefulness of [ 18 F]FDG PET/CT in such cases. In patients with suspected recurrent ovarian cancer implied in radiological findings, [ 18 F]FDG PET/CT results in most cases differed from the original results of imaging examination. Our results showed high accuracy of [ 18 F]FDG PET/CT in the evaluation of recurrent ovarian cancer and presented this diagnostic method as a useful tool in detecting and differentiating suspected lesions in this group of patients.

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Section: Originalsupporting

confidence: 79%

The value of [18F]FDG PET/CT examination in the detection and differentiation of recurrent ovarian cancer

Kosinska,

Misiewicz,

Kalita

et al. 2023

Nucl. Med. Rev.

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“…Tuberculosis after CAR T-cell therapy was also reported in a letter to editor in which a 9-year-old girl developed tuberculosis 5 months after CAR-T therapy 10 . It is well-known that tuberculosis infection can lead to false-positive in interpretation of 18 F-FDG PET/CT images 11–15 . Tuberculosis infection usually slowly develops, and thus it is unusual to have symptomatic tuberculosis infection within 1 month of CAR-T therapy in a patient who was not infected before the treatment.…”

mentioning

confidence: 87%

“…10 It is well-known that tuberculosis infection can lead to false-positive in interpretation of 18 F-FDG PET/CT images. [11][12][13][14][15] Tuberculosis infection usually slowly develops, and thus it is unusual to have symptomatic tuberculosis infection within 1 month of CAR-T therapy in a patient who was not infected before the treatment. Awareness of such possibility is important in accurately interpreting FDG PET/CT images when it is used to monitor efficacy of CAR-T therapy.…”

Section: Figurementioning

confidence: 99%

New Onset of Tuberculosis Complicating FDG PET/CT Evaluation in Patient With Recent Chimeric Antigen Receptor T-Cell Therapy

Wang

Yang

Wang³

et al. 2023

Clin Nucl Med

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A 16-year-old adolescent girl with CD19 chimeric antigen receptor (CAR) T-cell therapy for acute lymphoblastic leukemia experienced new onset of the fever. 18 F-FDG PET/CT studies acquired at 1 and 2 months, respectively, after CAR-T, showed foci of abnormal activity in the mediastinal lymph nodes not seen on the study before therapy. However, these foci of abnormal activity were later proven due to newly developed tuberculosis after CAR T-cell therapy.

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Solitary Chest Wall Tuberculosis Mimicking a Malignancy Demonstrated on FDG PET/CT

Cited by 2 publications

References 16 publications

The value of [18F]FDG PET/CT examination in the detection and differentiation of recurrent ovarian cancer

The value of [18F]FDG PET/CT examination in the detection and differentiation of recurrent ovarian cancer

New Onset of Tuberculosis Complicating FDG PET/CT Evaluation in Patient With Recent Chimeric Antigen Receptor T-Cell Therapy

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