Solidly mounted resonator sensor for biomolecule detections

Han, Chengzhang; Wang, Xia; Zhao, Qi; Teng, Lihua; Zhang, Shuaiyi; Lv, Hao; Liu, Jing; Ma, Haoran; Wang, Yanping

doi:10.1039/c9ra01695c

Cited by 6 publications

(2 citation statements)

References 41 publications

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“…Another approach was demonstrated by Han et al that combined a Bragg acoustic reflector with an Au electrode and an aluminum nitride piezoelectric thin film, to develop a biosensor for anti-human IgG detection by immobilization of the human IgG antibody onto the modified Au electrode. The sensing platform was able to detect antihuman IgG concentrations smaller than 0.4 mg/mL [24]. The sensing platform presented in this work is able to detect the referenced target below to 0.1 µg/mL.…”

Section: Affinity and Slectivity Assaysmentioning

confidence: 85%

Label-Free Anti-Human IgG Biosensor Based on Chemical Modification of a Long Period Fiber Grating Surface

Mendes

Coelho

Pereira

et al. 2021

The 1st International Electronic Conference on Chemical Sensors and Analytical Chemistry

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This work introduces a method specially developed to produce a biorecognition element based on modified Stöber silica nanoparticles by the covalent immobilization of the human IgG. The sensing structure is based on long period fiber gratings (LPFG), specially developed to allow the interaction of the electromagnetic wave with the target analytes through its evanescent field. The surface was modified by the immobilization of the IgG-modified nanoparticles serving has recognition elements for specific target molecules. The resulting configuration was tested in the presence of anti-human IgG, recording the refractometric response of the modified LPFG in contact with different amounts of analyte. The selectivity of the sensor was also assessed.

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Section: Affinity and Slectivity Assaysmentioning

confidence: 85%

Label-Free Anti-Human IgG Biosensor Based on Chemical Modification of a Long Period Fiber Grating Surface

Mendes

Coelho

Pereira

et al. 2021

The 1st International Electronic Conference on Chemical Sensors and Analytical Chemistry

View full text Add to dashboard Cite

show abstract

“…[1][2][3][4] As bulk acoustic wave (BAW) devices operating in the GHz range, FBARs have attracted much attention due to their small size, high operating frequency and potential applications in high-frequency communication and mass-sensitive sensor areas. [5][6][7][8] As a kind of FBAR, solidly mounted resonators (SMRs) are composed of a piezoelectric layer sandwiched between electrodes and Bragg reector consisting of alternating high and low acoustic impedance quarter-wavelength thick dielectric or metallic layers. 9,10 The SMR, with good mechanical strength and excellent acoustic properties, and being closer to CMOS integration, was therefore chosen in this work.…”

Section: Introductionmentioning

confidence: 99%