Solid-pseudopapillary tumor of the pancreas: Clinical experience and literature review

Abstract

SPT is a rare tumor that behaves less aggressively than other pancreatic tumor. However, in cases with local invasion, long-term follow up is advisable.

Solid Pseudopapillary Tumor of the Pancreas: A Single-center Experience and Review of the Literature

“…This tumor was first described by by SPT but it is considered very rare (21). Since SPT's first description in literature, various names have been used to describe this rare lesion, such as solid and cystic tumor of the pancreas, papillary-cystic tumor, solid and papillary epithelial neoplasm and Frantz tumor (3,4,22). In 1996, the World Health Organization renamed this tumor as SPT for the international histologic classification of tumor of the exocrine pancreas (22,23).…”

“…Angiography, although not routinely indicated, may demonstrate scarce or lack of blood vessels in the pancreatic tumor and help delineate the mass from other involved and adjacent structures (4). Barium meal examinations usually show deformity of the stomach, enlargement of the duodenal loop and narrowing of the duodenal lumen, caused by external pressure from the mass on the organs' wall; these findings, however, are not pathognomonic for setting the diagnosis.…”

“…pancreatic neoplasms (3)(4)(5)(6)(7). However, it has been recognized with increasing frequency in recent years as noted by Stömmer et al (8).…”

“…Of note, the origin of these neoplasms has not yet been clarified. These neoplasms have a low malignant potential and usually occur in adolescent girls and young women (age range=8-67 years; mean=35); men are rarely affected (4,(9)(10)(11)(12). Although it is thought that these tumors usually affect people of Asian or African-American origin, SPT can occur in patients of all races (13,14).…”

Solid Pseudopapillary Neoplasm of the Pancreas Associated with Familial Adenomatous Polyposis

“…SPN patients treated with complete surgical resection have a good prognosis (21). However, approximately 15-20% of cases of SPN manifest with malignant behavior, including perineural or vascular infiltration and metastasis (22,23). Fatal cases of recurrence have been reported (24).…”