Solid-phase microextraction with on-fiber derivatization for the analysis of anti-inflammatory drugs in water samples

Rodrı́guez, I.; Carpinteiro, J.; Quintana, José Benito; Carro, A.M.; Lorenzo, R.A.; Cela, R.

doi:10.1016/j.chroma.2003.10.049

Cited by 110 publications

(14 citation statements)

References 19 publications

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“…7.4). Reagents used for this purpose have high volatility, such as silylation reagents including n-methyl-n-(trimethylsilyl)trifluoroacetamide (MSTFA) [38], nmethyl-n-(tert-butyldimethylsilyl) trifluoroacetamide (MTBSTFA) [39], hexamethyldisilazane [40], n-methylbis(trifluoroacetamide) [41], pentafluorobenzoyl chloride [42], or trifluoroacetic anhydride [43]. After DI SPME with appropriate fiber, on-fiber post-derivatization with silylation reagents have mainly focused on the analysis of aliphatic amines, phenolic compounds, acid pesticides, …”

Section: On-fiber Post-derivatizationmentioning

confidence: 99%

“…In vial derivatization, acetic anhydride [18,91,159], and dimethyl sulfate/NaOH [17,82] were used to derivatizate phenolic compounds; sodium tetrahydroborate (NaBH 4 ), NaBPr 4 , and NaBEt 4 were used to derivatizate organometallic compounds [29, 31, 86, 87, 89, 127-129, 138-140, 160]. Silylating reagents such as MTBSTFA, BSTFA, and MSTFA were widely used for different kinds of chemicals in on-fiber post-derivatization [39,45,53,54,56,[161][162][163]. Pentafluorophenylhydrazine (PFPH) and PFBHA were widely used for on-fiber in situ derivatization of aldehyde compounds [27,105,164,165].…”

Section: Watermentioning

confidence: 99%

“…On-fiber post-derivatization is widely used for anatoxin-a [112,113], p-hydroxybenzoic acid (parabens) [56], phenolic compounds [45,53,161,162], β-agonist clenbuterol [40], anti-inflammatory drugs [39], dimethylamine [103], salicylate-and benzophenone-type UV filters [163], phenoxy acid herbicides, and dicamba [54]. On-fiber in situ derivatization is used for compounds isocyanates [35] and trimethylamine (TMA) [102].…”

Section: Watermentioning

confidence: 99%

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Application of Solid-Phase Microextraction Combined with Derivatization for Polar Compound Sampling in Environmental Analysis

Yang¹,

Luan²

2016

Solid Phase Microextraction

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Solid-phase microextraction (SPME) is a solvent-free sample preparation technique using a fused-silica fiber coated with an appropriate stationary phase. Derivatization is often necessary to determine substances with poor chromatographic behavior, high reactivity, and/or volatility or thermal instability. SPME derivatization technique can be operated under different combined modes and may be influenced by factors such as sample matrix, SPME, derivatization, and desorption condition. Combined with derivatization, HS-SPME, DI-SPME, membrane-protected SPME, and in-tube SPME have been applied to the analysis of a vast amount of chemicals, i.e., aldehydes and acetone, amines, organic acids, phenolic compounds, pesticide, metal and organic metal species, and pharmaceutical and personal care products (PPCPs) in a wide range of environmental matrices, including air, water, soil, and sediment samples. This chapter reviews the mode and method development of the derivatization technique, the derivatization reagents, and reaction mechanism, as well as its applications in environmental analysis.

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Section: On-fiber Post-derivatizationmentioning

confidence: 99%

Section: Watermentioning

confidence: 99%

Section: Watermentioning

confidence: 99%

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Application of Solid-Phase Microextraction Combined with Derivatization for Polar Compound Sampling in Environmental Analysis

Yang¹,

Luan²

2016

Solid Phase Microextraction

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“…In the recent years, the presence of pharmaceuticals in WWTPs effluents have been reported [11][12][13][14][15][16]. Concentration of pharmaceuticals in the environment, their temporary evolution and their possible synergic and antagonist effects depend not only in the amount discharged from WWTPs but also on the geographical area and climate conditions.…”

Section: Introductionmentioning

confidence: 99%

“…Accurate and sensitive methods are necessary for the determination of pharmaceuticals in environmental samples, in order to, evaluate the amount of these compounds that are being discharged into the aquatic environment. HPLC-MS [12,13,[17][18][19][20][21][22] and GC-MS [14,15,23] have been used to determine pharmaceutical in water samples. However, when analyzing highly contaminated samples, such as wastewater, a suppression of the electrospray ionization is likely to occur.…”

Section: Introductionmentioning

confidence: 99%

Rapid HPLC Method for Monitoring Relevant Residues of Pharmaceuticals Products in Environmental Samples

Rodríguez¹,

Salcedo²,

Fernández³

2011

AJAC

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This work presents a multi-residue analytical method based on solid phase extraction (SPE) followed by high-performance liquid chromatographic (HPLC) with diode array (DAD) detection for the simultaneous determination of a group of pharmaceutical products that include ten antidepressants and three anticanceri- genic in environmental samples (water and soil). Baseline separation of the studied compounds was obtained on an ultrabase C18 (4.6 mm i.d. × 150 mm, 5 μm particle) column using acetonitrile:phosphate buffer pH 2.5 (35:65 v/v) as mobile phase with a flow rate of 1.5 mL/min. Different aspects including linearity, accuracy, precision and detection and quantification limits were examined in order to validate the proposed method. Detection limits between 1 and 50 ng/mL were obtained for all the target compounds. This method was ap- plied to the analysis of environmental samples as waters and soils of different precedence. Prior, the HPLC determination the samples were purified and enriched using SPE or liquid-liquid extraction (LLE) of the tar- get compounds

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New Sample Preparation Strategies for Analytical Determinations

Quintana

Ramil

Rodil

et al. 2014

Encyclopedia of Analytical Chemistry

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Sample preparation techniques have experienced an explosive development during the past decades. Procedural approached that uses minimal sample amounts reducing to the limit and sometimes eliminating completely the use of toxic and/or environmentally unfriendly solvents and reagents have emerged as standard in the analytical laboratory. At the same time, significant improvements in sensitivity and selectivity have appeared. This article revisited the principal developments of sample preparation methods for analytical determinations as produced recently. The approach is systematic, classifying the procedures into two broad groups: methods based on equilibrium and exhaustive methods. In each case, the principal methods are revisited with a brief description about the principles and chemistry involved and some examples in each case. A large number of bibliographic references allow a deeper study on each case, when necessary.

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Solid-phase microextraction with on-fiber derivatization for the analysis of anti-inflammatory drugs in water samples

Cited by 110 publications

References 19 publications

Application of Solid-Phase Microextraction Combined with Derivatization for Polar Compound Sampling in Environmental Analysis

Application of Solid-Phase Microextraction Combined with Derivatization for Polar Compound Sampling in Environmental Analysis

Rapid HPLC Method for Monitoring Relevant Residues of Pharmaceuticals Products in Environmental Samples

New Sample Preparation Strategies for Analytical Determinations

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