Solid-Phase Adsorption of Curcumin from Turmeric Extracts by Lamellar Solids and Magnesium Oxide and Hydroxide

Fiorito, Serena; Epifano, Francesco; Preziuso, Francesca; Palumbo, Lucia; Marchetti, Lorenzo; Bastianini, Maria; Cardellini, Fabio; Spogli, Roberto; Genovese, Salvatore

doi:10.1007/s12161-020-01931-z

Cited by 8 publications

(3 citation statements)

References 27 publications

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“…This seems to greatly facilitate the adsorption and consequently the interaction with organic compounds, like gentiopicroside ( 1 ) and amarogentin ( 2 ), presumably due to interactions of a lipophilic nature or of the van der Waals type. The present results confirm a trend exhibited by these same materials (especially by Mg Al azelate, entry E) with other classes of natural products like anthraquinones, phenolic acids, flavonoids, purine alkaloids, diarylheptanoids, capsaicinoids, oxyprenylated coumarins, apocarotenoids, and anthocyanins …”

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confidence: 88%

Leaves of Yellow Gentian (Gentiana lutea) as an Alternative Source of Bitter Secoiridoid Glycosides

et al. 2022

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In a search for methods of manufacturing bitter principles from Gentiana lutea, mainly represented by gentiopicroside (1) and amarogentin (2), as an alternative to extraction from the roots of this plant, in this short communication it is shown that the leaves of this plant can be regarded as an additional source of such phytochemicals. Extraction of G. lutea leaves was coupled to solid-phase adsorption by differently structured solids as a separation technology step, providing a selective isolation of both these secondary metabolites in good to excellent yields. Thus, the extraction of bitter secoiridoids can be achieved in an equivalent or improved way rather than processing the roots of G. lutea while preserving the biodiversity of the species.

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confidence: 88%

Leaves of Yellow Gentian (Gentiana lutea) as an Alternative Source of Bitter Secoiridoid Glycosides

et al. 2022

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“…37 LDHs are ideally biocompatible and have several industrial applications to produce a plethora of cosmetic, nutraceutical, and pharmaceutical preparations. 38 During the last three years, lamellar solids have found extensive use in phytochemistry and have been shown to be tremendously efficient for the selective extraction of classes of plant secondary metabolites like flavonoids, catechins, alkaloids, 39 diarylheptanoids, 40 bitter secoiridoids, 41,42 capsaicinoids, 43 oxyprenylated coumarins, 44 tetraterpenes, 45 and anthocyans. 46 48 The pattern of adsorption was practically the same, allowing good to excellent recovery of anthraquinones (all or some) by using the same two sorbents mentioned above in addition to magnesium aluminum azelate, which also displayed good performance.…”

Section: Lamellar Solidsmentioning

confidence: 99%

Solid‐phase adsorption methodologies of naturally occurring anthraquinones: A review

Palumbo

Fiorito

Epifano

et al. 2023

Phytochemical Analysis

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Introduction: Solid-phase extraction applied to plant matrices is nowadays a wellvalidated technique allowing to concentrate and purify different secondary metabolites. Several classes of phytochemicals have been selectively extracted by this methodology. During the last decade attention has been focused on biologically active anthraquinones from numerous sources like edible, healthy, and medicinal plants. Objectives: The aim of this review is to provide a detailed literature survey of the solid-phase adsorption methodologies for the extraction of natural anthraquinones reported so far and to discuss and propose future directions in this field of research. Materials and Methods: Substructure search was performed in the SciFinder Scholar, PubMed, Medline, and Scopus databases. Results: The first report about application of solid-phase adsorption for the purification of anthraquinones appeared in the literature in 2002. From this date, and in particular during recent years, the most notable examples included the use of chitin-and chitosan-based polymers, of molecularly imprinted polymers, of coated magnetic nanoparticles, of miniaturized matrix solid-phase dispersion, of functionalized resins, of differently structured lamellar solids, and finally of vortex-synchronized matrix solid-phase dispersion. Conclusions:The herein detailed solid-phase adsorption methodologies are powerful tools to selectively extract natural anthraquinones and/or provide anthraquinoneenriched phytopreparations. Nevertheless, many other important methods have been applied to synthetic anthraquinones (e.g., azo dyes). These could be conveniently employed also for natural anthranoids. Studies in this field are discussed in this review article.

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“…[19] [20] The curcumin in turmeric has been widely studied for its anti-inflammatory properties. [14] [15] Based on the results of the survey and the theory of problems in patients with gouty arthritis or gout, the authors solve this problem by using computation in exploring the active compounds in the database. [7][30] The author's goal in this case is to maintain uric acid levels in the blood.…”

Section: Literature Reviewmentioning

confidence: 99%

Bioinformatics Study of Turmeric (Curcuma Domestica Val) Againts Arthritis Gout Disease

et al. 2022

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Degenerative diseases are developing today. One of them is gouty arthritis, also known as gout. This disease is very common in society. In Indonesia, the prevalence of gouty arthritis is 34-32 years old. According to a report from the Padang City Health Office in 2018, gouty arthritis was ranked the 4th highest disease in the city of Padang after gastritis. The highest prevalence was in North Padang District with 400 sufferers and Alai Health Center ranked 2nd with 118 cases. Gouty arthritis is characterized by high levels of uric acid in the blood (hyperuricemia). Arthritis is rarely fatal, but can be stressful for patients. The therapy used is anti-inflammatory drugs with many side effects. Turmeric (Curcuma longa) is one of the herbal plants that has the potential to treat rheumatism and gout. Turmeric (Curcuma domestica Val) is an herbal plant with anti-inflammatory properties for gouty arthritis. The large old turmeric rhizome is often used as medicine. Turmeric contains the active ingredient curcumin. It has been extensively studied as an anti-inflammatory drug. This is because curcumin can inhibit the protein Cyclooxygenase-2 (COX-2). COX-2 is an enzyme that mediates inflammation. Therefore, the curcumin in turmeric has a potential anti-inflammatory effect and can be used as the basis for the treatment of artritis gout.

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Solid-Phase Adsorption of Curcumin from Turmeric Extracts by Lamellar Solids and Magnesium Oxide and Hydroxide

Cited by 8 publications

References 27 publications

Leaves of Yellow Gentian (Gentiana lutea) as an Alternative Source of Bitter Secoiridoid Glycosides

Leaves of Yellow Gentian (Gentiana lutea) as an Alternative Source of Bitter Secoiridoid Glycosides

Solid‐phase adsorption methodologies of naturally occurring anthraquinones: A review

Bioinformatics Study of Turmeric (Curcuma Domestica Val) Againts Arthritis Gout Disease

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