Solid-Contact Ion-Selective Electrodes for Histamine Determination

Abstract

Solid-contact ion-selective electrodes for histamine (HA) determination were fabricated and studied. Gold wire (0.5 mm diameter) was coated with poly(3,4-ethlenedioxythiophene) doped with poly(styrenesulfonate) (PEDOT:PSS) as a solid conductive layer. The polyvinyl chloride matrix embedded with 5,10,15,20-tetraphenyl(porphyrinato)iron(iii) chloride as an ionophore, 2-nitrophenyloctyl ether as a plasticizer and potassium tetrakis(p-chlorophenyl) borate as an ion exchanger was used to cover the PEDOT:PSS layer as a selective membrane. The characteristics of the HA electrodes were also investigated. The detection limit of 8.58 × 10−6 M, the fast response time of less than 5 s, the good reproducibility, the long-term stability and the selectivity in the presence of common interferences in biological fluids were satisfactory. The electrode also performed stably in the pH range of 7–8 and the temperature range of 35–41 °C. Additionally, the recovery rate of 99.7% in artificial cerebrospinal fluid showed the potential for the electrode to be used in biological applications.

Ion-Selective Electrodes in the Food Industry: Development Trends in the Potentiometric Determination of Ionic Pollutants

“…As such, keeping low potentiometric noise rates is key to ensuring accurate measurements and percentage recovery values close to 100%. Both liquid membrane and all-solid-state ion-selective electrodes can be applied to the detection of a wide range of charged compounds, from cations and anions, up to small molecules such as histamines [39], and even pharmaceuticals like salbutamol [40]. To date, there are over 100 different ionic species that can be analysed using ion-selective electrodes, including potentially toxic compounds, such as heavy metals and oxyanions.…”

New Materials Used for the Development of Anion-Selective Electrodes—A Review

“…This makes them easier to store and transport, which is especially important for field measurements. [11,12]. The electrodes are easy to obtain in small sizes and in any shape.…”