2013
DOI: 10.1016/j.msec.2012.11.039
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Sol–gel derived nanoscale bioactive glass (NBG) particles reinforced poly(ε-caprolactone) composites for bone tissue engineering

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Cited by 51 publications
(33 citation statements)
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“…On the other hand, the water droplet can be spread easier on the more porous surface of membrane, which results in higher hydrophilicity [41]. It was previously shown that bioactive glass particles, as a hydrophilic material, remarkably improve the hydrophilicity of PCL matrix [9,18]. Nevertheless, a more pronounced effect was observed for composites containing smaller bioactive glass particles due to their homogenous distribution in the PCL matrix and thus uniform exposition on the surfaces [42,43].…”
Section: Discussionmentioning
confidence: 99%
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“…On the other hand, the water droplet can be spread easier on the more porous surface of membrane, which results in higher hydrophilicity [41]. It was previously shown that bioactive glass particles, as a hydrophilic material, remarkably improve the hydrophilicity of PCL matrix [9,18]. Nevertheless, a more pronounced effect was observed for composites containing smaller bioactive glass particles due to their homogenous distribution in the PCL matrix and thus uniform exposition on the surfaces [42,43].…”
Section: Discussionmentioning
confidence: 99%
“…Porous biomaterials for TE have to meet several requirements: (1) uniformly distributed and interconnected highly porous structure with suitable pore size and shape to provide adequate space for cells seeding or growth, blood vessel ingrowth and flow transport of nutrients and metabolic waste; (2) biodegradable or bioresorbable with a controllable degradation and resorption rate, appropriate to match tissue growth in vivo and with non-cytotoxic degradation products; (3) suitable surface topography, chemistry and wettability for cell attachment, proliferation and differentiation; (4) mechanical properties matching those of the tissues at the site of implantation [2,6,7]. Furthermore, materials for bone tissue engineering (BTE) should possess bone-bonding ability, as well as osteoconductive/osteoinductive properties [8,9].…”
Section: Introductionmentioning
confidence: 99%
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