Soft-Tissue Metastases From Esophageal Cancer

Abiad, Jad M. El; Hales, Russell K.; Levin, Adam S.; Morris, Carol D.

doi:10.1007/s11605-019-04160-w

Cited by 10 publications

(7 citation statements)

References 29 publications

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“…should be treated individually. When planning treatment, the clinical stage of primary disease, the patient's performance status and general condition, as well as prognostic factors should be considered [6]. Based on literature review, it can be seen that the majority of patients were treated with chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

“…In other patients, radiotherapy and/or surgical resection of the metastasis was used. It seems that patients with single metastasis in skeletal muscle should be resected or irradiated, whereas patients with multiple metastases should receive chemotherapy [6][7][8].…”

Section: Discussionmentioning

confidence: 99%

“…Diagnosis of metastases in skeletal muscle is usually associated with terminal stage of the disease and very poor prognosis [9]. The average survival time from the diagnosis of metastasis is 7.5-9 months [6,8,10,12]. For comparison, the average survival time from the diagnosis of primary stage IV oesophageal cancer is 13 months [6].…”

Section: Discussionmentioning

confidence: 99%

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Skeletal muscle metastasis from oesophageal adenocarcinoma — case report and literature review

Rakowska

2019

Oncol Clin Pract

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The most common sites of metastases from oesophageal carcinoma are lymph nodes, liver, lungs, and bones. Metastases to skeletal muscles are very rare and are characterised by extremely poor prognosis. A 62-year-old man with advanced oesophageal adenocarcinoma underwent chemoradiotherapy. More than six months after the primary diagnosis, the patient presented with distant solitary metastasis to the skeletal muscle of the left lower leg. He complained of severe pain and swelling of the left lower leg. Radiological and pathological examination confirmed metastatic character of the lesion. The patient was qualified for radiotherapy. Metastases to skeletal muscle are very rare, and no guidelines have been established for the treatment for these patients. It seems that chemotherapy and radiotherapy can be considered as the best treatment modality for these patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Skeletal muscle metastasis from oesophageal adenocarcinoma — case report and literature review

Rakowska

2019

Oncol Clin Pract

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“…Information in the literature regarding the clinical presentation, treatment, and oncological outcomes of cancer soft tissue metastases is limited, primarily reported in the form of case reports 9 , 10 , 11 , 12 and case series. 1 , 2 , 4 , 13 , 14 , 15 This is why there is still controversy surrounding the optimal therapeutic approach and expected oncological outcomes.…”

Section: Introductionmentioning

confidence: 99%

Surgical resection of soft tissue metastasis in cancers: A single‐center study of 77 cases over a 7‐year period

Ye,

Hu,

Sun

et al. 2023

Cancer Medicine

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IntroductionSoft tissue metastasis (STM) of cancers, encompassing skeletal muscle and subcutaneous tissue metastasis, is less common due to unique homeostatic conditions. With longer life expectancy and the advent of new imaging modalities, clinical physicians will increasingly encounter and manage such cases. This study retrospectively reviewed cases of STM in visceral cancers who underwent surgery at Fudan University Shanghai Cancer Center over a 7‐year period.MethodsData were collected through a comprehensive review of medical records, including demographic variables, primary tumor characteristics, surgical data, tumor pathology, and outcomes. Survival analysis was performed using Kaplan–Meier curves.ResultsThe study included 77 cases with a median follow‐up period of 854 days. The most common primary tumor sites were the lung (11) and breast (10). The abdominal wall was the most frequent site of metastasis. The combination of visceral metastasis, age over 52 years, and a history of primary tumor correlates with a poorer prognosis. Surgical‐related metastases are associated with a higher degree of differentiation. Additionally, we have identified a better prognosis for patients with cancer of unknown primary (CUP) exhibiting potential resectable soft tissue metastases.ConclusionThe combination of visceral metastasis, age over 52 years, and a history of primary tumor suggest a poorer prognosis. While no significant impact on survival was observed for patients with lymph node metastasis. Surgical‐related metastases are associated with a higher degree of differentiation. CUP patients with potentially resectable soft tissue metastases should be considered for surgical intervention.

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“…It is less common for EAC metastases to disseminate to soft tissues with roughly 3.5% of non-conventional metastases occurring in cutaneous tissues and skeletal muscles [3]. However, there is an increasing body of literature that describes metastatic EAC to soft tissue sites [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

A Role for Esophagectomy in Patients with Definitively Treated Solitary Oligometastasis and Worsening Dysphagia: A Case Series

Am¹,

Bs²,

Jd³

2021

JJGH

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Soft-Tissue Metastases From Esophageal Cancer

Cited by 10 publications

References 29 publications

Skeletal muscle metastasis from oesophageal adenocarcinoma — case report and literature review

Skeletal muscle metastasis from oesophageal adenocarcinoma — case report and literature review

Surgical resection of soft tissue metastasis in cancers: A single‐center study of 77 cases over a 7‐year period

A Role for Esophagectomy in Patients with Definitively Treated Solitary Oligometastasis and Worsening Dysphagia: A Case Series

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