Heterotopic ossification (HO) is a diverse pathologic process, defined as the formation of extraskeletal bone in muscle and soft tissues. HO can be conceptualized as a tissue repair process gone awry and is a common complication of trauma and surgery. This comprehensive review seeks to synthesize the clinical, pathoetiologic, and basic biologic features of HO, including nongenetic and genetic forms. First, the clinical features, radiographic appearance, histopathologic diagnosis, and current methods of treatment are discussed. Next, current concepts regarding the mechanistic bases for HO are discussed, including the putative cell types responsible for HO formation, the inflammatory milieu and other prerequisite “niche” factors for HO initiation and propagation, and currently available animal models for the study of HO of this common and potentially devastating condition. © 2019 The Authors. JBMR Plus published by Wiley Periodicals, Inc. on behalf of American Society for Bone and Mineral Research.

Virtualize your mission-critical video and voice applications and increase the flexibility, manageability, and efficiency of your deployment. The software evolutionThe Polycom ® RealPresence ® Platform is the intelligent infrastructure that makes video collaboration always available to everyone across any network, protocol, application or device of choice. With the rise of the virtualized datacenter, Polycom has evolved the components of the RealPresence Platform to support virtual software deployment strategies-increasing the flexibility, manageability, and efficiency of your video deployment. The RealPresence Platform can now can now be deployed instantly as software, making video and voice collaboration simple and scalable in any environment.

The coronavirus disease 2019 (COVID-19) pandemic has prompted rapid restructuring of the health-care system in an effort to stop the spread of the virus and to treat patients who are acutely ill with COVID-19, while continuing to provide outpatient care for the remainder of patients. To help control spread of this pandemic, many centers, including total joint arthroplasty clinics, have boosted telemedicine capability to care for patients who would typically be seen in person in outpatient settings. We review key components relevant to the establishment and effective use of telemedicine, focused on patient education, practice logistics, technological considerations, and sensitive patient health informationeassociated compliance factors, which are necessary to provide care remotely for total joint arthroplasty patients.