Soft tissue giant cell tumor of low malignant potential of the neck: a case report and review of the literature

Abstract

Giant cell tumor of soft parts is a rare tumor that is clinically and histologically similar to giant cell tumor of the bone. We present a 53-year-old female with a giant cell tumor of low malignant potential arising from the neck. The clinicopathological features and the importance of immunohistochemistry in the differential diagnosis with other giant cell rich tumors was discussed. Key Words: Soft tissue neoplasms, Giant cell tumors, Head and neck neoplasms ÖZYumuşak dokunun dev hücreli tümörü, kemiğin dev hücreli tümörüne klinik ve histolojik olarak benzeyen, nadir görülen bir tümördür. Burada, 53 yaşındaki kadın hastada boyunundan köken alan düşük malign potansiyelli dev hücreli tümör olgusu sunuldu. Klinikopatolojik özellikleri ve diğer dev hücreden zengin tümörlerden ayırıcı tanısında immünohistokimyanın önemi tartışıldı.Anahtar Sözcükler: Yumuşak doku tümörleri, dev hücreli tümörler, Baş boyun tümörleri

A Pilot Evaluation of Magnetic Resonance Imaging Characteristics Seen With Primary Soft Tissue Giant Cell Tumor in 2 patients

“…In our study, we used a conventional MRI and DWI approach to investigate two cases of soft tissue giant cell tumor in the limb. The radiologic abnormalities of all lesions were limited to soft tissue without obvious calcification or bone erosion, which are frequently observed at the periphery of the GCT-ST tumors [2][3][4][5][6][7] . In addition, all lesions on MRI presented with solid masses, and blurry boundaries on the upper and lower edges.…”

“…In the present study, all lesions were significantly big (maximum lesion size ranged from 4.0 cm to 6.0cm) and were located in the superficial areas of extremities or trunk. This type of lesion is commonly observed in GCT-ST, but it can also be found in the deep soft tissues of head, neck and retroperitomeum region [2][3][4][5][6][7][8][9][10] . Unlike deep-seated masses, size criteria (i.e.…”

“…Clinically, primary GCT-ST mainly affects young to middle-age adults [4][5][6][7][8][9][10][11]16] . Here we reported two cases with GCT-ST: the first was an elder man who was asymptomatic and had a benign clinical course; the other one was a young woman who presented with ill-circumscribed multinodular mass were included in the differential diagnosis.…”

“…Histologically, GCT-ST lesions bear a close resemblance to their bony counterparts, giant cell tumor of bone. Most of the existing reports are pathological and clinical studies, while the imaging aspects have only been reported in the cases of adjacent bone or with atypical cystic degeneration [2][3][4][5][6][7][8][9][10] . There is only one case report on intravoxel incoherent motion (IVIM) DWI of juxtacortical mass [2] .…”

A Pilot Evaluation of Magnetic Resonance Imaging Characteristics Seen With Primary Soft Tissue Giant Cell Tumor in 2 patients

“…Histologically, GCT-ST lesions bear a close resemblance to their bony counterparts, giant cell tumor of bone. Most of the existing reports are pathological and clinical studies, while the imaging aspects have only been reported in the cases of adjacent bone or with atypical cystic degeneration [2][3][4][5][6][7][8][9][10][11] . With regard to MR or ultrasonography imaging features, superficial masses can be further identified based on facial edema, skin thickening, skin contact, internal hemorrhage or necrosis and lobulation of the mass [12][13][14][15] .…”