Sodium tetradecyl sulphate sclerotherapy for treating venous malformations of the oral and pharyngeal regions in children

Stimpson, Paul; Hewitt, Richard; Barnacle, Alex; Roebuck, Derek J.; Hartley, Ben

doi:10.1016/j.ijporl.2012.01.019

Cited by 36 publications

(34 citation statements)

References 20 publications

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“…Alternatively, the lower efficacy of sclerotherapy of larger caliber or faster flow lesions was seen as a result of less sclerosant agent making contact with the endothelial cells of the lesional walls. The conclusions for this study are consistent with the previous literature in which the best results were [21] used 3 % STS foam to treat 12 patients who had VnM in the head and neck. They found that a single treatment may be adequate for small lesions, but the injections may be safely repeated until a satisfactory result is obtained in large lesions.…”

Section: Discussionsupporting

confidence: 91%

The Use of Sodium Tetradecyl Sulphate for the Treatment of Venous Malformations of the Head and Neck

Alakailly

Kummoona

Quereshy

et al. 2014

J. Maxillofac. Oral Surg.

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Introduction Vascular malformations have devastating cosmetic effects in addition to being associated with pain and bleeding. Sclerotherapy has been used as an effective therapeutic modality for the management of vascular malformations. The purpose of this case series is to describe our clinical experience of using sodium tetradecyl sulphate (STS) 3 % in the treatment of venous malformation lesions of head and neck. Materials and Methods Thirteen patients were included in this study (three male and ten female; age range between 8 months and 54 years; mean age 18.2 years, ±SD 15.71). The patients were treated by 3 % STS intralesional injections. Of the thirteen patients treated, complete resolution occurred in four patients (28.57 %), a good response occurred in five patients (35.7 %), a moderate response in two patients (14.28 %), a mild response in two patients (14.28 %) and no response in one patient (7.14 %). The side effects encountered in all patients were pain and edema after injection which was controlled by oral analgesics and an intramuscular injection of dexamethasone. In addition, two patients developed a superficial ulceration (11.76 %) which healed uneventfully, and one patient developed ecchymosis after injection (5.88 %). Conclusion Sclerotherapy with 3 % STS is a simple, safe, and effective modality for the treatment of venous malformations.

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Section: Discussionsupporting

confidence: 91%

The Use of Sodium Tetradecyl Sulphate for the Treatment of Venous Malformations of the Head and Neck

Alakailly

Kummoona

Quereshy

et al. 2014

J. Maxillofac. Oral Surg.

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“…However, the improved safety profile of these agents comes at the cost of lower potency than ethanol. In previous studies, STS has been associated with success rates of 43-84%, 52,[54][55][56] whereas polidocanol has similarly reported ranges of 45-84%. 57,58 Importantly, the definition of an adequate response as well as the lesion size, anatomical location and patient population is highly variable among previous studies, and, thus, it is difficult to ascertain the true efficacy of STS and polidocanol for VM treatment.…”

Section: Capillary Malformationsmentioning

confidence: 92%

Vascular anomalies: classification, imaging characteristics and implications for interventional radiology treatment approaches

Mulligan

Prajapati²,

Martin

et al. 2014

BJR

160

132

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The term vascular anomaly represents a broad spectrum of vascular pathology, including proliferating vascular tumours and vascular malformations. While the treatment of most vascular anomalies is multifactorial, interventional radiology procedures, including embolic therapy, sclerotherapy and laser coagulation among others, are playing an increasingly important role in vascular anomaly management. This review discusses the diagnosis and treatment of common vascular malformations, with emphasis on the technique, efficacy and complications of different interventional radiology procedures.

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“…Surgical excision was the original treatment of choice and may still offer the best curative option if it can be performed safely [1]. However, surgical intervention to remove large pharyngeal VMs may be difficult and invasive, and resection by a wide neck incision may induce abnormal functioning of the pharynx.…”

Section: Discussionmentioning

confidence: 99%

“…Venous malformations (VMs) are the most frequent type of vascular malformation [1]. They typically appear as a bluish discoloration of the skin, lips, or inside of the mouth and tend to increase in size with actions such as crying, pushing, or other maneuvers that increase pressure in the venous system.…”

Section: Introductionmentioning

confidence: 99%

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Treatment of a Large Pharyngeal Venous Malformation using Transoral Sclerotherapy

et al. 2017

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Summary: Management of venous malformation (VM) in the pharynx is challenging because of difficulties in needle access and the presence of nerves as well as other critical anatomical structures around the lesion. We describe the successful treatment of a large pharyngeal VM using transoral sclerotherapy. The patient, a 21-yearold male, visited our hospital for sclerotherapy treatment consultation after complaining of difficulty in swallowing because of a pharyngeal VM. Transoral sclerotherapy was successful, and the symptoms showed complete alleviation. Using a flat detector-equipped angiographic C-arm CT (CACT) enabled the precise assessment of sclerosant placement, facilitating safer sclerotherapy in the pharynx.

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Sodium tetradecyl sulphate sclerotherapy for treating venous malformations of the oral and pharyngeal regions in children

Cited by 36 publications

References 20 publications

The Use of Sodium Tetradecyl Sulphate for the Treatment of Venous Malformations of the Head and Neck

The Use of Sodium Tetradecyl Sulphate for the Treatment of Venous Malformations of the Head and Neck

Vascular anomalies: classification, imaging characteristics and implications for interventional radiology treatment approaches

Treatment of a Large Pharyngeal Venous Malformation using Transoral Sclerotherapy

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