Sodium bisulfate feed additive aids broilers in growth and intestinal health during a coccidiosis challenge

Chadwick, Elle; Rahimi, Shaban; Grimes, J. L.; Pitts, John S.; Beckstead, Robert B.

doi:10.1016/j.psj.2020.07.027

Cited by 9 publications

(3 citation statements)

References 27 publications

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“…Although obvious bloody diarrhea was not achieved in the current study, fecal moisture content was increased after 6 dpi. Potentially, E. tenella damaged enterocytes in the ceca and modulated microbiota, and this caused electrolyte imbalance in the ceca which may explain the modulated ileal and fecal moisture contents in the current study [ 39 ]. Moreover, ceca play a crucial role in water absorption [ 40 ], and water absorption ability of the ceca of birds infected with E. tenella would be limited potentially due to thickened mucosa layer in the current study.…”

Section: Discussionmentioning

confidence: 99%

Effects of Eimeria tenella Infection on Key Parameters for Feed Efficiency in Broiler Chickens

Choi

Tompkins

et al. 2021

Animals

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The purpose of the study was to investigate effects of different inoculation dosages of E. tenella on growth performance, gastrointestinal permeability, oocyst shedding, intestinal morphology, fecal consistency, ileal apparent digestibility, antioxidant capacity, and cecal VFA profile in broiler chickens. Five different dosages (T0: 0, T1: 6250, T2: 12,500, T3: 25,000, and T4: 50,000) of E. tenella oocysts were inoculated via oral gavage to fourteen-day-old broilers. Inoculation of E. tenella linearly increased FCR (p < 0.05), and feed intake was quadratically increased on 6 days post-infection (dpi; p = 0.08) and 7 dpi (p = 0.09). Cecal lesion score of each treatment was T0: 0; T1: 0.39 ± 0.14; T2: 0.93 ± 0.21; T3: 1.25 ± 0.16; and T4: 1.58 ± 0.2. Cecal total VFA production was linearly reduced due to E. tenella infection on 6 dpi (p < 0.01). E. tenella infection deepened cecal crypts depth on 6 dpi (CD; p < 0.05). Gastrointestinal permeability tended to be linearly increased (p = 0.07). E. tenella infection tended to linearly reduce duodenal VH (p = 0.1) and jejunal VH on 9 dpi (p = 0.09). Different dosages of E. tenella modulated the tendency of fecal moisture content and oocyst shedding. Therefore, E. tenella infection impaired feed efficiency and small intestinal health mainly by reducing cecal VFA production and deepening cecal CD in broilers.

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Section: Discussionmentioning

confidence: 99%

Effects of Eimeria tenella Infection on Key Parameters for Feed Efficiency in Broiler Chickens

Choi

Tompkins

et al. 2021

Animals

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“…It also improves feed conversion efficiency in broilers (Ruiz-Feria et al, 2011). Adding sodium bisulfate to feed will help coccidia-challenged birds to maintain intestinal integrity and enhance their growth but does not affect parasite oocyst shedding (Chadwick et al, 2020).…”

Section: Mineralsmentioning

confidence: 99%

Nutritional Supplements for the Control of Avian Coccidiosis – A Review

Alsayeqh

Abbas

2023

Annals of Animal Science

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Coccidiosis is acclaimed as the most prevalent enteric parasitic ailment of poultry. It is caused by an apicomplexan protozoon of the genus Eimeria, which resides in chicken intestinal epithelium leading to intestinal damage. As a result, bloody droppings are there, feed efficiency is reduced, the growth rate is impaired, and egg production is temporarily decreased. Treatment and prevention of coccidiosis are primarily accomplished by inoculating live vaccines and administering anticoccidial drugs. Due to anticoccidials’ continuous and excessive use, the mounting issue is drug resistant Eimeria strains. The poultry industry has managed resistance-related issues by suggesting shuttle and rotation schemes. Furthermore, new drugs have also been developed and introduced, but it takes a long time and causes cost inflation in the poultry industry. Moreover, government disallows growth promoters and drugs at sub-therapeutic doses in poultry due to increased concerns about the drug residues in poultry products. These constraints have motivated scientists to work on alternative ways to control coccidiosis effectively, safely, and sustainably. Using nutritional supplements is a novel way to solve the constraints mentioned above. The intriguing aspects of using dietary supplements against coccidiosis are that they reduce the risk of drug-resistant pathogen strains, ensure healthy, nutritious poultry products, have less reliance on synthetic drugs, and are typically considered environmentally safe. Furthermore, they improve productivity, enhance nonspecific immunity, preventing oxidation of fats (acting as antioxidants) and inflammation (acting as an anti-inflammatory). The present manuscript focuses on the efficacy, possible mechanism of action, applications, and different facets of nutrition supplements (such as organic acids, minerals, vitamins, probiotics, essential oils, amino acids, dietary nucleotides, feed enzymes, and yeast derivatives) as feed additive for treating poultry coccidiosis.

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“…(9) IP reduced by 0.5% glutamine (1) Murugesan et al. (2014) ; (2) Goossens et al., 2018 ; (3) Chadwick et al (2020) ; (4) Teng et al (2020) ; (5) Schneiders et al (2020) (6) dos Santos et al, 2020 ; (7) Pham et al. (2020) ; (8) Song et al.…”

Section: Introductionmentioning

confidence: 99%

Current experimental models, assessment and dietary modulations of intestinal permeability in broiler chickens

Gilani¹,

Chrystal

Barekatain

2021

Animal Nutrition

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Maintaining and optimising the intestinal barrier (IB) function in poultry has important implications for the health and performance of the birds. As a key aspect of the IB, intestinal permeability (IP) is mainly controlled by complex junctional proteins called tight junction proteins (TJ) that link enterocytes together. The disruption of TJ is associated with increased gut leakage with possible subsequent implications for bacterial translocation, intestinal inflammation, compromised health and performance of the birds. Despite considerable data being available for other species, research on IP in broiler chickens and in general avian species is still an understudied topic. This paper reviews the available literature with a specific focus on IP in broiler chickens with consideration given to practical factors affecting the IP, current assessment methods, markers and nutritional modulation of IP. Several experimental models to induce gut leakage are discussed including pathogens, rye-based diets, feed deprivation and stress-inducing agents such as exogenous glucocorticoids and heat stress. Although various markers including fluorescein isothiocyanate dextran, expression of TJ and bacterial translocation have been widely utilized to study IP, recent studies have identified a number of excreta biomarkers to evaluate intestinal integrity, in particular non-invasive IP. Although the research on various nutrients and feed additives to potentially modulate IP is still at an early stage, the most promising outcomes are anticipated for probiotics, prebiotics, amino acids and those feed ingredients, nutrients and additives with anti-inflammatory properties. Considerable research gaps are identified for the mechanistic mode of action of various nutrients to influence IP under different experimental models. The modulation of IP through various strategies (i.e. nutritional manipulation of diet) may be regarded as a new frontier for disease prevention and improving the health and performance of poultry particularly in an antibiotic-free production system.

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Sodium bisulfate feed additive aids broilers in growth and intestinal health during a coccidiosis challenge

Cited by 9 publications

References 27 publications

Effects of Eimeria tenella Infection on Key Parameters for Feed Efficiency in Broiler Chickens

Effects of Eimeria tenella Infection on Key Parameters for Feed Efficiency in Broiler Chickens

Nutritional Supplements for the Control of Avian Coccidiosis – A Review

Current experimental models, assessment and dietary modulations of intestinal permeability in broiler chickens

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