Socio‐economic, behavioural, (neuro)psychological and clinical determinants of HRQoL in people living with HIV in Belgium: a pilot study

Degroote, Sophie; Vogelaers, Dirk; Vermeir, Peter; Mariman, An; Rick, Ann De; Gucht, Beatrijs Van Der; Pelgrom, Jolanda; Wanzeele, Filip Van; Verhofstede, Chris; Vandijck, Dominique

doi:10.7448/ias.16.1.18643

Cited by 50 publications

(56 citation statements)

References 49 publications

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“…Furthermore, employment seemed to positively influence health-related quality of life. 5 The present study aimed to explore experiences of PLHIV in the workplace concerning disclosure and adherence to ART.…”

Section: Introductionmentioning

confidence: 99%

HIV disclosure in the workplace

Degroote

Vogelaers

Koeck

et al. 2014

Acta Clinica Belgica

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Objectives: As HIV is currently a chronic and manageable disease, an increasing amount of people living with HIV (PLHIV) are (again) active on the labour market. Since research on this topic is scarce, this study aimed to explore experiences of PLHIV in the workplace, especially concerning disclosure and adherence to antiretroviral therapy. Methods: A questionnaire was developed and validated in collaboration with Sensoa (Flemish expertise centre for sexual health) and participants were recruited using flyers and announcements on websites. Results: A total of 54 PLHIV completed the questionnaire, among whom 50 (92.6%) males. Half of the participants did not disclose their HIV status in the workplace, mostly due to being afraid of social or professional consequences. Those who disclosed, reported no changes in the workplace or even reported receiving more empathy. A minority of participants have to take antiretroviral medication at work and they reported no particular problems related to medication intake. Conclusion: Despite improved solidarity and information campaigns, many PLHIV still do not disclose their HIV status in the workplace, most frequently due to fear for discrimination. More actions are warranted, as well as addressing possible self-stigma. Adherence to antiretroviral therapy in the workplace posed little or no problems

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Section: Introductionmentioning

confidence: 99%

HIV disclosure in the workplace

Degroote

Vogelaers

Koeck

et al. 2014

Acta Clinica Belgica

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“…Se describe menor score de CVRS asociado a menor nivel de escolaridad (3)(4)(5)(6)(7)(8)(9) , depresión/ansiedad (3,6,(9)(10)(11)(12)(13)(14)(15)(16) , preocupación financiera, falta de soporte económico o social (6,9,10,11,(17)(18)(19)(20)(21)(22) , presencia de síntomas (14,(21)(22)(23) , estigma o preocupación por la confidencialidad (12,17,23,24) , consumo de drogas y alcohol (4,5) , comorbilidades (4,5,25) , bajo nivel de confianza o pobre relacionamiento con el staff médico y menor accesibilidad al sistema de salud (11,17,25) .…”

Section: Introductionunclassified

“…En cuanto al género, predominantemente los estudios encuentran peor CVRS entre mujeres en los resultados globales o en algunos dominios de las escalas utilizadas (5)(6)(7)(8)10,11,(14)(15)(16)18,(22)(23)(24)(25)(26)(27)(28)(29) . Mientras que el impacto de la orientación sexual, específicamente hombres que tienen sexo con hombres (HSH), se muestra con resultados variables probablemente por influencia de los diferentes contextos culturales (5,30,31) .…”

Section: Introductionunclassified

“…El espectro va desde peor score en CVRS en personas con bajo recuento de CD4 (6,22,26,33) y mayor score entre aquellos con mejor inmunidad (4,31) , hasta aquellos que no encuentran asociación (5,10,11,19,22,34) . Son escasas las evidencias que muestran asociación de la CV indetectable con mejoría (34) o peoría (5) con el score de CVRS.…”

Section: Introductionunclassified

“…Por el contrario, una amplia mayoría no establece asociación alguna (10,11,13,15,23) . Los hallazgos respecto al uso de TARV también difieren.…”

Section: Introductionunclassified

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Calidad de vida relacionada a la salud en personas con VIH y factores asociados

Alonso

Dalchiele

Rouco

et al. 2018

RMU

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ResumenIntroducción: aunque existe una mejoría significativa en la sobrevida consecuencia del impacto del tratamiento antirretroviral (TARV), numerosos estudios demuestran que existe una afectación de la calidad de vida relacionada a la salud (CVRS) en personas con virus de inmunodeficiencia humana (VIH). Objetivo: evaluar CVRS en personas con VIH y variables socio-demográficas y clínicas asociados, con énfasis en la adherencia al TARV. Método: estudio transversal de una muestra no probabilística de personas con VIH, mayores de 18 años, recibiendo TARV, asistidas en el subsector público en un período de 24 meses. Se aplicó la encuesta MOS-HIV SF30 (CVRS). Se aplicó el cuestionario SMAQ para evaluar adherencia. Resultados: se incluyeron 101 personas. El cuestionario MOS-HIV SF30 mostró fiabilidad y buena consistencia interna. El score global de CVRS fue 71,71±17,76. Fue peor el score global y en algunas dimensiones en pacientes con carga viral indetectable: funcionamiento físico, p=0,016; energía/fatiga, p=0,008; calidad de vida percibida, p=0,025. En mujeres el score fue peor en dolor, p=0,034; funcionamiento físico, p=0,006; funcionamiento social, p=0,031; salud mental, p=0,040. El score fue significativamente mejor en algunos dominios entre adherentes (salud general percibida, p=0,027; funcionamiento social, p=0,030); en varones gay/bisexuales (dolor, p=0,025; actividad diaria, p=0,028); entre quienes tuvieron relaciones sexuales en el último mes (salud general percibida, p=0,011). Conclusiones: el score global de CVRS fue bueno a pesar de ser una población con múltiples vulnerabilidades. Si bien la adherencia se relacionó a mejor percepción de CVRS en algunos dominios, no tuvo impacto en el score global. La carga viral indetectable no fue predictor de mejor CVRS, lo que reafirma que los parámetros biológicos aislados no dan cuenta de la complejidad de la salud percibida.

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Socio‐economic status and time trends associated with early ART initiation following primary HIV infection in Montreal, Canada: 1996 to 2015

et al. 2018

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IntroductionGuidelines regarding antiretroviral therapy (ART) initiation in HIV infection have varied over time, with the 2015 World Health Organization recommendation suggesting ART initiation at the time of diagnosis regardless of CD4 T‐cell counts. Herein, we investigated the influence of socio‐demographic and clinical factors in addition to time trends on early ART initiation among participants of the Montreal Primary HIV Infection Study.MethodsThe Montreal Primary HIV Infection Study is a prospective cohort established in three community medical centres (CMCs) and two university medical centres (UMCs). Recently diagnosed HIV‐infected adults were categorized as receiving early (vs. delayed) ART if ART was initiated within 180 days of the baseline visit. Associations between early ART initiation and socio‐demographic, socio‐economic and behavioural information were examined. Independent associations of factors linked with early ART initiation were determined using multivariable binary logistic regression analysis.ResultsA total of 348 participants had a documented date of HIV acquisition of <180 days. The median interquartile range (IQR) age of participants was 35 (28; 42) years and the majority were male (96%), having paid employment (63%), men who have sex with men (MSM) (78%) and one to four sexual partners in the last three months (70%). Participants presented with a median IQR HIV plasma viral load of 4.6 (3.7; 5.3) log10 copies/ml, CD4 count of 510 (387; 660) cells/μl and were recruited in CMCs (52%) or UMCs (48%). Early ART initiation was observed in 47% of the participants and the trend followed a V‐shaped curve with peaks in 1996 to 1997 (89%) and 2013 to 2015 (88%) with a dip in 2007 to 2009 (22%). Multivariable analyses showed that having a paid employment adjusted odds ratio (aOR: 2.43; 95% CI: 1.19, 4.95), lower CD4 count (aOR per 50 cell increase: 0.93; 95% CI: 0.87, 0.99) and care at UMCs (aOR: 2.03; 95% CI: 1.06 to 3.90) were independently associated with early ART initiation.ConclusionsEarly ART initiation during primary HIV infection was associated with diminished biological prognostic factors and calendar time mirroring evolution of treatment guidelines. In addition, socio‐economic factors such as having a paid employment, contribute to early ART initiation in the context of universal access to care in Canada.

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Socio‐economic, behavioural, (neuro)psychological and clinical determinants of HRQoL in people living with HIV in Belgium: a pilot study

Cited by 50 publications

References 49 publications

HIV disclosure in the workplace

HIV disclosure in the workplace

Calidad de vida relacionada a la salud en personas con VIH y factores asociados

Socio‐economic status and time trends associated with early ART initiation following primary HIV infection in Montreal, Canada: 1996 to 2015

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