Socio-demographic, economic and health profile of adults with sickle-cell disease

Amaral, Júlia Lamese; Almeida, Nívea Aparecida de; Santos, Paula Silveira; Oliveira, Patrícia Peres de; Lanza, Fernanda Moura

doi:10.15253/2175-6783.2015000300002

Cited by 5 publications

(12 citation statements)

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“…The patients' profiles in this study are compatible with those described in the literature, with a predominance of homozygous disease (SS), female sex, non-white individuals, and young individuals [9,12,13]. However, most patients in this study reported a low frequency of pain crises, which is different from that reported in previous studies [9,14,15].…”

Section: Discussionsupporting

confidence: 83%

Chronic osteo-articular changes in patients with sickle cell disease

et al. 2021

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Background Sickle cell disease (SCD) is an autosomal recessive genetic disease in which a mutation occurs in the β-globin chain gene, resulting in abnormal hemoglobin levels. In an environment with reduced oxygen concentration, red blood cells change their conformation, resulting in chronic hemolysis and consequent anemia and vaso-occlusive crises with injuries to several organs, with a significant impairment of the osteoarticular system. This study aimed to verify the chronic osteoarticular alterations and their association with clinical and laboratory characteristics of patients with SCD with a more severe phenotype (SS and Sβ0), on a steady-state fasis. Methods Fifty-five patients were referred to a medical consultation with a specialized assessment of the locomotor system, followed by laboratory tests and radiographic examinations. Results In total, 74.5% patients had hemoglobinopathy SS; 67.3% were female; and 78.2% were non-whites. The mean patient age was 30.5 years. Most patients (61.8%) reported up to three crises per year, with a predominance of high-intensity pain (65.5%). Radiographic alterations were present in 80% patients. A total of 140 lesions were identified, most which were located in the spine, femur, and shoulders. Most lesions were osteonecrosis and osteoarthritis and were statistically associated with the non-use of hydroxyurea. Conclusions There was a high prevalence of chronic osteoarticular alterations, which was statistically associated only with the non-regular use of hydroxyurea.

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Section: Discussionsupporting

confidence: 83%

Chronic osteo-articular changes in patients with sickle cell disease

et al. 2021

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“…Levenson et al [ 10 ] found that most of their samples were females, had high school education, were from 25 to 34 and were single. Amaral et al [ 11 ] also found that among their sample, the highest frequency was recorded for patients who were married, were females, were between 30 and 39 years old and had attained high school education. Finally, Asnani et al [ 12 ] reported that the mean age of the participants in their study was 30 years old, most of whom were females and most had attained secondary/high school level of education.…”

Section: Introductionmentioning

confidence: 99%

Socio-demographic characteristics and psychosocial consequences of sickle cell disease: the case of patients in a public hospital in Ghana

Adzika

Glozah

Ayim-Aboagye

et al. 2017

J Health Popul Nutr

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BackgroundSickle cell disease (SCD) is of major public health concern globally, with majority of patients living in Africa. Despite its relevance, there is a dearth of research to determine the socio-demographic distribution and psychosocial impact of SCD in Ghana. The objective of this study was to examine the socio-demographic distribution and psychosocial consequences of SCD among patients in Ghana and to assess their quality of life and coping mechanisms.MethodsA cross-sectional research design was used that involved the completion of questionnaires on socio-demographic characteristics, quality of life, coping mechanisms, anxiety and depression. Participants were 387 male and female patients attending a sickle cell clinic in a public hospital.ResultsResults showed that majority of the patients were single, female, less than 39 years old and had attained secondary school level of education or less. Also, patients were more satisfied by the presence of love, friends and relatives as well as home, community and neighbourhood environment. While pains of varied nature and severity were the major reasons for attending hospital in SCD condition, going to the hospital as well as having faith in God was the most frequently reported mechanisms for coping with an unbearable SCD attacks. Results of multiple regression analysis showed that some socio-demographic and quality of life indicators had strong associations with anxiety and/or depression.ConclusionsIt is recommended that a holistic intervention strategy incorporating psychosocial dimensions should be considered in the treatment and management of SCD.

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“…Como também foi demonstrado no presente estudo em relação à raça/cor, a literatura aponta a predominância de DF em indivíduos pardos e/ou pretos. Historicamente, em decorrência da associação ao período colonial e ao processo de escravidão, vários autores relacionam a prevalência de DF na população negra (Felix et al, 2015;Amaral et al, 2015;Almeida, Camargo e Felzemburgh, 2012;Brasil, 2015 Palermo et al (2002), a situação socioeconômica dos indivíduos acometidos por DF seria um preditor significativo de incapacidade funcional.…”

Section: Resultsunclassified

Perfil epidemiológico e clínico de usuários do centro municipal de referência de indivíduos com doença falciforme em Feira de Santana/Bahia

Silva

Barbosa

Silva

et al. 2021

RSD

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A Doença Falciforme (DF) é uma hemoglobinopatia de predominância da hemoglobina S nas hemácias, de caráter genético. O objetivo deste trabalho foi descrever o perfil epidemiológico e clínico de 64 usuários com DF do Centro Municipal de Referência à pessoa com DF no município de Feira de Santana/BA, no período de novembro de 2016 a março de 2017. O presente estudo foi submetido e aprovado por um comitê de ética em pesquisa. A predominância foi do sexo feminino, raça/cor foi parda/preta, escolaridade menor que 8 anos de estudo, renda menor ou igual um salário mínimo e sem ocupação. Quanto às condições clínicas, a maioria teve diagnóstico médico de anemia falciforme e a descoberta da doença ocorreu via teste do pezinho. Embora a maioria não possuísse comorbidades, um elevado número de participantes apresentou algum tipo de complicação referente à doença, sendo mais frequentes as crises álgicas, pneumonia, síndrome torácica aguda e sequestro esplênico. Os resultados apresentados podem ser usados pelo serviço como instrumento para traçar um plano de cuidado para essa população de acordo com o perfil epidemiológico e clínico dos usuários, bem como, reforça a importância de estratégias como a educação em saúde, para minimizar a ocorrência das complicações.

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Socio-demographic, economic and health profile of adults with sickle-cell disease

Cited by 5 publications

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Chronic osteo-articular changes in patients with sickle cell disease

Chronic osteo-articular changes in patients with sickle cell disease

Socio-demographic characteristics and psychosocial consequences of sickle cell disease: the case of patients in a public hospital in Ghana

Perfil epidemiológico e clínico de usuários do centro municipal de referência de indivíduos com doença falciforme em Feira de Santana/Bahia

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