Socio-demographic and Clinical Characteristics of Patient with Thyroid Cancer

Abstract

Background: Thyroid cancer is the most common malignant disease in endocrine system. It is an emerging public health issue associated with burden on the family, community and the nation. The aim of this study is to determine the socio-demographic and clinical characteristics of patient with thyroid cancer attending in tertiary hospital.
 Methods: This cross sectional study was conducted among 246 thyroid cancer patients in two tertiary hospitals of Dhaka city from 01 July 2018 to 30 June 2019. The subjects were selected purposively following specific selection criteria and maintaining ethical issues. Data were collected by face to face interview using a semi-structured questionnaire and checklist. Data were analyzed by the statistical package for the social science (SPSS) version 23.
 Results: This study revealed that majority (74.4%) of respondents was female, married (72%), housewife (61.4%), rural respondent (41.1%) and had primary education (69%). Mean (± SD) age of the respondent was 37.85(±12.20) years (Range 14-70 years) and mean (± SD) monthly family income was Tk. 17681(±10602). Out of 246 cases, 204 (82.9%) was papillary and 42 (17.1%) was follicular carcinoma. Various clinical presentations included visible neck swelling in 225 (91.5%), swollen lymph node in 103 (41.9%), pain 90 (36.6%), Difficulties in swallowing 87 (35.4%), Hoarseness of voice in 141 (57.3%), cough along with swelling 47(19.1%), Difficulties in breathing due to swelling in 13(5.3%) of the patients.
 Conclusion: Incidence of thyroid cancer has increased worldwide specially in female patients in 3rd and 4th decades of life. As thyroid cancer is a growing public health problem in Bangladesh, proper screening and early diagnostic facilities at all level should be available to measure its actual burden in the country.
 Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 54-58

Significance of P63 Expression in Papillary and Follicular Thyroid Carcinoma

“…The maximum number of patients (61.4%) in this study was in between 30-39 years age group. Similar pattern of age distribution was observed by Hossain et al 12 , Islam et al 13 and Hussain et al 14 The mean age of patients of this study was 40.86 ± 6.57 years. Different studies by Akhtar et al 15 , Mokhtari et al 16 , Merchant D 17 , Hussain et al 14 and Islam et al 13 showed different mean age like 45, 42.4, 41.8, 38 and 32.7.…”

“…In this study, female (70.5%) predominance was observed over male (29.5%) making a male & female ratio 1:2.4 which is comparable to the study conducted by Hossain et al 18 , Merchant D 17 and Islam et al 13 with male to female ratio of 1:3,1:2.2 and 1:2.3. This was also in agreement with studies of Mokhtari et al 16 , Sarfraz et al 19 , Rahman et al 20 and Akhtar et al 15 In the present study, papillary thyroid carcinoma was the most frequent histologic type among studied thyroid lesions and it comprises 88.6% which is comparable to the local study done by Islam et al 13 where 68% of all thyroid carcinomas were papillary thyroid carcinoma.…”