Social responsibilities of a pediatric journal: considerations and future directions

Yang, Lingge; Wang, Xianjun; Qi, Qi; Xu, Siyun; Xie, Yicheng; Zhao, Zhengyan; Shu, Qiang

doi:10.1007/s12519-021-00416-1

Cited by 2 publications

(3 citation statements)

References 8 publications

(7 reference statements)

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“…Children with severe COVID-19 may develop neurologic manifestations (up to 22% among 1695 hospitalized children and adolescents) ( 32 ), and occasionally acute disseminated encephalomyelitis ( 33 ), acute transverse myelitis ( 8 ), respiratory failure ( 31 ), myocarditis ( 34 ), shock ( 31 ), ocular symptoms ( 35 , 36 ) acute renal failure ( 37 ), and multi-organ system failure ( 31 ). In the large series of 1695 hospitalized children and adolescents with COVID-19, neurologic involvement occurred was significantly more frequent among patients with underlying neurologic disorders ( 32 ).…”

Section: Methodsmentioning

confidence: 99%

COVID-19 in Children: Where do we Stand?

Nikolopoulou

Maltezou

2022

Archives of Medical Research

181

132

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From the beginning of the coronavirus disease 2019 (COVID-19) pandemic it became evident that children infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain mostly asymptomatic or mildly symptomatic. We reviewed the epidemiologic and clinical features of children with SARS-CoV-2 infection. The true prevalence of asymptomatic SARS-CoV-2 infection is most likely underestimated, as asymptomatic children are less frequently tested. Serologic surveys indicate that half of children tested positive for SARS-CoV-2 report no symptoms. Anosmia/ageusia is not frequent in children but it is the strongest predictor of a positive SARS-CoV-2 test. In general, children with COVID-19 are at lower risk of hospitalization and life-threatening complications. Nevertheless, cases of severe disease or a post-infectious multisystem hyperinflammatory syndrome named multisystem inflammatory syndrome in children (MIS-C) have been described. Rarely children with severe COVID-19 develop neurologic complications. In addition, studies indicate that school closures have a limited impact on SARS-CoV-2 transmission, much less than other social distancing measures. The past months new SARS-CoV-2 variants emerged with higher transmissibility and an increased impact on morbidity and deaths. The role of children in the transmission dynamics of these variants must be elucidated. Lastly, preliminary results from COVID-19 vaccine trials indicate very good efficacy and tolerability in children. Very recently the United States Centers for Disease Control and Prevention and other public health authorities recommend vaccination of children 12 years or older to protect them but mostly to contribute to the achievement of herd immunity.

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Section: Methodsmentioning

confidence: 99%

COVID-19 in Children: Where do we Stand?

Nikolopoulou

Maltezou

2022

Archives of Medical Research

181

132

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“…The most frequently reported ocular manifestation of COVID-19 is conjunctivitis. 3 – 5 Other nonsight-threatening complications include eyelid dermatitis, 6 keratoconjunctivitis, 7 episcleritis, 8 – 10 and isolated retinal findings. 11 – 13 There has been 1 report on bilateral posterior scleritis in a COVID-19 patient with multisystemic involvement including renal insufficiency, bilateral pulmonary embolism, mesenteric ischemia, and encephalitis.…”

Section: Discussionmentioning

confidence: 99%

“… 2 Its most common ocular manifestation is conjunctivitis. 3 – 5 Eyelid dermatitis, 6 keratoconjunctivitis, 7 episcleritis, 8 – 10 isolated retinal findings, 11 – 13 and posterior scleritis 14 are among other reported ocular complications of COVID-19. In a span of 4 months since July 2020, we observed 6 cases with anterior scleritis, a rare ocular disease, in our emergency department (2 cases with confirmed COVID-19 and 4 cases with negative laboratory test, but positive COVID-19 family members).…”

mentioning

confidence: 99%

Anterior Scleritis Manifesting After Coronavirus Disease 2019: A Report of Two Cases

Feizi

Meshksar

Naderi

et al. 2021

Cornea

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Purpose: The purpose of this study was to report 2 patients with anterior scleritis manifesting after coronavirus disease 2019 (COVID-19). Methods: The patients with confirmed COVID-19 developed anterior scleritis after their systemic symptoms were markedly improved. A thorough systemic workup identified no underlying autoimmune diseases. Ocular characteristics and safety and efficacy of systemic immunosuppressive therapy were evaluated. Results: Case 1 was a 67-year-old woman who presented with necrotizing anterior scleritis in both eyes 3 weeks after the onset of COVID-19. One-week treatment with topical betamethasone and oral prednisolone (65 mg daily) did not result in improvement, so she was started on intravenous cyclophosphamide and subcutaneous adalimumab in addition to oral prednisolone. Necrotizing scleritis was gradually improved over 3 months. Case 2 was a 33-year-old man who presented with sectoral anterior scleritis in his right eye 2 weeks after the onset of COVID-19. He was started on topical betamethasone and oral prednisolone (85 mg daily). One week later, all signs and symptoms disappeared, and topical and oral corticosteroids were gradually tapered off over 2 weeks. There was no recurrence of respiratory symptoms or active scleritis in any cases after discontinuation of treatment. Conclusions: These cases suggest that COVID-19 can be associated with anterior scleritis, which responds to immunosuppressive and biologic agents. Ophthalmologists should consider anterior scleritis in patients with COVID-19 who present with ocular pain and redness during the convalescent phase of the illness.

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Social responsibilities of a pediatric journal: considerations and future directions

Cited by 2 publications

References 8 publications

COVID-19 in Children: Where do we Stand?

COVID-19 in Children: Where do we Stand?

Anterior Scleritis Manifesting After Coronavirus Disease 2019: A Report of Two Cases

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