Social burden of people with the migraine diagnosis in Japan: evidence from a population-based cross-sectional survey

Igarashi, Hisaka; Ueda, Kaname; Jung, Sung-Eun; Chen, Zhihong; Chen, Yirong; Nakamura, Tomomi

doi:10.1136/bmjopen-2020-038987

Cited by 16 publications

(12 citation statements)

References 30 publications

(47 reference statements)

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“…Igarashi et al . 25 reported presenteeism of 32.73% and absenteeism of 6.95% in patients diagnosed with migraine, and the same decline in work performance in axillary hyperhidrosis patients as observed in our survey. Sruamsiri et al .…”

Section: Discussionsupporting

confidence: 91%

“…Furthermore, the annual societal loss associated with productivity loss was ¥2.5 trillion (approximately ¥208.3 billion/month). Igarashi et al25 reported presenteeism of 32.73% and absenteeism of 6.95% in patients diagnosed with migraine, and the same decline in work performance in axillary hyperhidrosis patients as observed in our survey. Sruamsiri et al26 conducted a Web-based survey on 500 pa-…”

supporting

confidence: 89%

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Cost‐of‐illness study for axillary hyperhidrosis in Japan

Murota

Fujimoto²,

Oshima

et al. 2021

The Journal of Dermatology

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Section: Discussionsupporting

confidence: 91%

supporting

confidence: 89%

Cost‐of‐illness study for axillary hyperhidrosis in Japan

Murota

Fujimoto²,

Oshima

et al. 2021

The Journal of Dermatology

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“…Their result indicates that 16% of workforce presenteeism may be due to migraine with a cost of US $240 billion dollars per year. Furthermore, according to the Japan National Health and Wellness Survey of pooled commercial data, migraine patients have been reported to experience significantly higher presenteeism than controls in Japan [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

Disability, quality of life, productivity impairment and employer costs of migraine in the workplace

et al. 2021

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Background Migraine is the leading cause of days lost due to disability in the world among people less than 50 years of age. There is a paucity of evidence on the impact of migraine and other headache disorders and the cost and productivity losses in the workplace. Methods Employee population survey assessed prevalence, characteristics, and disability of headache disorders at a Japanese information technology company. This study was supported by the World Health Organization Western Pacific Region Office and International Headache Society. Results 2458 (1963men, 495 women) out of 2494 responded to the survey that utilized ICHD-3 beta criteria. Among these, 13% (205 male/123 female) had migraine (M), 53% (1093 male/207 female) had tension-type headache (TTH) and 4% (61 male/27 female) had migraine and TTH (M/TTH). The number of days when productivity at work was reduced by half or more because of headache was significantly higher in migraine compared to TTH. The norm-based scoring of SF-12v2 was significantly lower in M/TTH and M than TTH. The economic loss due to absenteeism for migraine was calculated to be $ 238.3US$/year/person for day-off and 90.2US$/year/person for half-day off using migraine disability assessment score (MIDAS). The economic loss due to presenteeism for migraine was calculated to be $ 375.4US$/year/person using MIDAS and 2217US$/year/person using work productivity and activity impairment questionnaire (WPAI). Furthermore, estimated cost of productivity loss associated with presenteeism using WPAI was calculated at 21.3 billion US$/year in Japan as a whole. Conclusions This study revealed a high prevalence and disease burden among employees with migraine that is associated with substantial losses in productivity and employer cost. These results support the development and implementation of workplace programs to improve migraine management in the workplace and reduce the burden and costs associated with lost workplace productivity.

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“…Impairment was greater in people with migraine in the OVERCOME (Japan) study than has been reported for people without migraine. In a direct comparison of Japanese people with and without migraine, using data from the Japan NHWS, those without migraine had total work impairment scores of only 20% and total activity impairment scores of 22% [ 12 ]. WPAI-M absenteeism scores in OVERCOME (Japan) ranged from 3.8% in the LFEM group to 6.2% in the CM group.…”

Section: Discussionmentioning

confidence: 99%

“…These surveys revealed a high burden of disease among Japanese people with migraine, including substantial proportions of people requiring bed rest during migraine attacks, experiencing moderate-to-severe impacts on social activity, requiring time off work, and experiencing a general perception of poor health [ 5 , 6 ]. More recently, an analysis of data from the Japan National Health and Wellness Survey (NHWS) in 2017 revealed that people with a migraine diagnosis had poorer health-related quality of life (HRQoL) and more impairment to work productivity than matched controls without migraine [ 12 , 13 ]. A recent workplace-based survey conducted in a Japanese information technology company revealed a high prevalence and burden of migraine among employees and substantial associated economic costs [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Burden of Migraine in Japan: Results of the ObserVational Survey of the Epidemiology, tReatment, and Care Of MigrainE (OVERCOME [Japan]) Study

Matsumori,

Ueda,

Komori

et al. 2021

Neurol Ther

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Introduction The ObserVational survey of the Epidemiology, tReatment, and Care Of MigrainE study in Japan (OVERCOME [Japan]) assessed the impact and burden of migraine in Japan. Methods OVERCOME (Japan) was a cross-sectional, observational, population-based web survey of Japanese people with migraine conducted between July and September 2020. The burden and impact of migraine were assessed using the Migraine Disability Assessment (MIDAS), Migraine-Specific Quality-of-Life Questionnaire (MSQ), Migraine Interictal Burden Scale (MIBS-4), and Work Productivity and Activity Impairment-Migraine scale. Results were stratified by average number of monthly headache days (0–3, 4–7, 8–14, ≥ 15). Results In total, 17,071 Japanese people with migraine completed the survey. Of these, 14,033 (82.2%) met International Classification of Headache Disorders, 3rd edition criteria for migraine and 9667 (56.6%) reported a physician diagnosis of migraine. Overall, 20.7% of respondents experienced moderate-to-severe disability (MIDAS). Moderate-to-severe interictal burden (MIBS-4) was experienced by 41.5% of respondents. MSQ scores in all domains were lowest in respondents with the most frequent headaches (≥ 15 monthly headache days) and highest in those with the lowest frequency headaches (≤ 3 monthly headache days), indicating poorer quality of life in those with more frequent headaches. Work time missed due to migraine (absenteeism) increased with increasing headache frequency, from 3.8 to 6.2%; presenteeism affected 29.8–49.9% of work time. Although migraine burden was greatest in people with the most frequent headaches, those with the lowest headache frequency still experienced substantial disability, interictal burden, and impacts on productivity and quality of life. There was also substantial unmet need for migraine care: 36.5% of respondents had ever hesitated to seek medical care for their headaches, and 89.8% had never used preventive medication. Conclusion In Japan, the burden of migraine and barriers to migraine care are substantial. Improving patient awareness and healthcare provider vigilance may help improve patient outcomes. Supplementary Information The online version contains supplementary material available at 10.1007/s40120-021-00305-9.

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Social burden of people with the migraine diagnosis in Japan: evidence from a population-based cross-sectional survey

Cited by 16 publications

References 30 publications

Cost‐of‐illness study for axillary hyperhidrosis in Japan

Cost‐of‐illness study for axillary hyperhidrosis in Japan

Disability, quality of life, productivity impairment and employer costs of migraine in the workplace

Burden of Migraine in Japan: Results of the ObserVational Survey of the Epidemiology, tReatment, and Care Of MigrainE (OVERCOME [Japan]) Study

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