Snowflake-Like Dendrimers via Site-Selective Synthesis of Dendrons

Abstract

[structure: see text] Snowflake-shaped dendrimers were prepared via site-selective synthesis of dendrons, where an attachment of encapsulating dendritic branches and an extension of phenylacetylenic units were alternatively manipulated on the structure of AB(2) (diethyltriazeno for A and bromo for B) substituted diphenylacetylene using a combination of Suzuki and Sonogashira cross-coupling reactions.

miR‐212 is downregulated and suppresses methyl‐CpG‐binding protein MeCP2 in human gastric cancer

“…Synthesis of complex structures without resorting to protection/deprotection strategies are valued in biology and nanoscale chemistry 1–4. For example, the preparation of elaborate dendritic species is also inevitably associated with a need for a selective functionalization 5, 6.…”

Synthesis of N‐aryl azetidine‐2,4‐diones and polymalonamides prepared from selective ring‐opening reactions

“…[1][2][3][4] For example, the preparation of elaborate dendritic species is also inevitably associated with a need for a selective functionalization. 5,6 Nevertheless, there is still a strong demand for improved procedures which could lead to the formation of a complex structure without need for protection/deprotection strategies.…”

Synthesis of Shape‐Persistent Polyal Dendrimers – Facile Entry to Polyene and Polyyne Dendrimers

“…As a result of this connectivity such dendrimers are dense on the periphery and relatively less dense at the core (e.g. starburst [21] and snowflake [22] type structures). The noteworthy feature of the present contribution is that the arene connectivity is 1,2,6 or 1,2,3 (compounds 4-11).…”