“…The literature describes isolated cases of successful use of drugs such as colchicine, cyclosporine, in liximab, etanercept, tumor necrosis factor alpha blockers, maxacalcitol, mizoribine, ketoconazole, tetracycline, minocycline, benzylpenicillin, vitamin E, azithromycin [11], doxycycline [8,12], adalimumab [13]. The ef icacy of systemic and topical glucocorticosteroids in elderly patients has also been reported [14,15].…”