2024
DOI: 10.1155/2024/8140483
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Treatment of Subcorneal Pustular Dermatosis without Dapsone: A Case Report and Review of the Literature

Lindsey J. Wanberg,
Brittney Schultz,
Amrita Goyal

Abstract: Subcorneal pustular dermatosis (SPD) is a rare neutrophilic dermatosis characterized by pustules on the trunk and intertriginous areas. While oral dapsone is the first-line treatment for SPD, alternative options are necessary for patients with glucose-6-phosphate dehydrogenase deficiency, drug hypersensitivity reactions, or refractory disease. To date, no consensus exists regarding next-best agents for SPD. In this report, we present a patient with significant SPD who developed dapsone hypersensitivity syndrom… Show more

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