Smooth-Muscle Tumors of the Skin

Montgomery, Hamilton; Winkelmann, R. K.

doi:10.1001/archderm.1959.01560130034004

Cited by 128 publications

(61 citation statements)

References 6 publications

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“…Pain can be spontaneous or can occur after exposure to cold, pressure, injury or emotional stress [1,12,13]. Our patients, however, reported little pain.…”

Section: Discussionmentioning

confidence: 74%

Familial Multiple Cutaneous Leiomyomas

Fernández‐Pugnaire

Delgado-Florencio

1995

Dermatology

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Background: Leiomyomas are rare, benign tumors that originate from the arrector muscle of hair follicles (cutaneous leiomyoma, piloleiomyoma), the tunica dartos of the scrotum and the mammillary muscle of the nipple (genital leiomyoma), and the smooth muscle of blood vessels (angioleiomyoma). Observations: We describe 6 members of a single family with mostly painful papulonodular cutaneous lesions on the limbs, trunk and face. Histological examination of sections stained with hematoxylin-eosin and Masson trichromic stain confirmed the diagnosis of leiomyoma. All affected women had also uterine myoma. Conclusion: Our observations support the concept that this entity is an autosomally inherited disorder.

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“…Pain can be spontaneous or can occur after exposure to cold, pressure, injury or emotional stress [1,12,13]. Our patients, however, reported little pain.…”

Section: Discussionmentioning

confidence: 74%

Familial Multiple Cutaneous Leiomyomas

Fernández‐Pugnaire

Delgado-Florencio

1995

Dermatology

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“…8 Among them, cutaneous LMS are rare, constituting 1-3% of all soft tissue sarcomas. They occur as solitary, slow growing lesion majority conceding with hair bearing areas of body.…”

Section: Discussionmentioning

confidence: 99%

Recurrent cutaneous leiomyosarcoma of the anterior abdominal wall: a rare tumor at an unusual site

2017

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<p class="abstract">Cutaneous leiomyosarcomas are uncommon neoplasms, accounting for 1-3% of all the soft tissue sarcomas. They encompass a variety of clinicopathological features that makes their diagnosis difficult. They are divided into various categories, as this division has an important prognostic implication. We describe a rare case of recurrent cutaneous leiomyosarcoma of the anterior abdominal wall in a 50 years old female. </p>

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“…Surgical excision, with or without skin grafts, is the gold standard for cure [15]. Destructive methods such as electrodessication, cryotherapy, or carbon-dioxide laser may be employed for small lesions, but there is little known benefit over excision, and unwanted scarring may occur [16,17]. Leiomyoma associated pain can be managed medically with drugs known to affect smooth muscle contraction, such as nitroglycerine, nifedipine, phenoxybenzamine, and doxazosin; recent reports also suggest the use of calcium channel blockers, botulinum toxin type A injections, antidepressants, and triamcinolone acetonide injections [18,19].…”

Section: Discussionmentioning

confidence: 99%

Pilar Leiomyoma Located on the Back: A Case Report

Elgendy¹,

Alshawadfy²,

Ali³

2015

J Clin Exp Dermatol Res

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Leiomyoma is a benign tumour commonly encountered in the genitourinary and gastrointestinal organs in adults. Cutaneous leiomyomas are rare benign tumors arising from the arrector pili muscle of hair follicles. Cutaneous leiomyomas are more likely to occur in adults than in children. We describe a case of a 30-year-old male who presented with skin-coloured masses on the back. A punch biopsy was performed. Under high-power examination, spindle cells with an eosinophilic cytoplasm were observed and immunohistochemical studies were performed; the cells stained strongly positive for smooth muscle actin (SMA). The patient was subsequently diagnosed with pilar leiomyoma and referred to a plastic surgeon for surgical treatment. A careful clinical assessment led to the correct diagnosis and therapy in the present case.

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Smooth-Muscle Tumors of the Skin

Cited by 128 publications

References 6 publications

Familial Multiple Cutaneous Leiomyomas

Familial Multiple Cutaneous Leiomyomas

Recurrent cutaneous leiomyosarcoma of the anterior abdominal wall: a rare tumor at an unusual site

Pilar Leiomyoma Located on the Back: A Case Report

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