Smoking cessation interventions among individuals in methadone maintenance: A brief review

Methadone’s effect on nAChRs—a link between methadone use and smoking?

“…The relative risk of death due to tobacco-related diseases is 1.8 times higher in substance abusers than in the general population [23]. Most methadone maintenance patients are willing to quit smoking [9,24] although smoking cessation is challenging for these patients, and they are less successful in their attempts to quit [25][26][27]. Quitting smoking is associated with greater abstinence from methadone use [28]; hence, a smoking cessation service offered by methadone clinics would be beneficial for these patients.…”

Early Quit Days Among Methadone-Maintained Smokers in a Smoking Cessation Trial

“…Yet, all of the smoking cessation pharmacotherapies that have been tested in opioiddependent persons have far lower quit rates (Mooney et al, 2008;Okoli et al, 2010;Reid et al, 2008;Shoptaw et al, 2002;Stein et al, 2006) than those reported in trials of nondrug users (Hurt et al, 1994;Mooney et al, 2008;Okoli et al, 2010;Reid et al, 2008;Shoptaw et al, 2002;Stead et al, 2008;Stein et al, 2006). Over the last two decades, there have been four fully powered randomized clinical trials (RCTs) involving smoking cessation interventions specifically with MMT smokers (Haug, Advance Access publication June 20, 2014 nicotine & tobacco research, volume 16, number 11 (november 2014) 1463-1469 early quit days among methadone-maintained smokers Svikis, & Diclemente, 2004;Shoptaw et al, 2002;Stein et al, 2006Stein et al, , 2013Story & Stark, 1991).…”

Smoking and Opioid Detoxification: Behavioral Changes and Response to Treatment

“…Many studies have assessed the effects of smoking in methadone-or buprenorphine-treated patients (for a review, see Guydish et al, 2011;Okoli et al, 2010), whereas clinical investigations have not examined how active smoking influences opioid use and withdrawal during detoxification. Although opioid detoxification cannot be considered an effective standalone treatment of OA, it is the primary point of contact with the treatment system for almost 50% of OA patients (Substance Abuse and Mental Health Services Administration, 2010).…”