2008
DOI: 10.1001/jama.2008.839
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Smoking and Colorectal Cancer

Abstract: Cigarette smoking is significantly associated with colorectal cancer incidence and mortality.

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Cited by 685 publications
(572 citation statements)
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References 116 publications
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“…Inherent adjustments for potential confounding by age, sex, and calendar year were, however, made in the analyses. Direct information on other risk factors, ie, alcohol overconsumption, 22 tobacco smoking, 23 physical inactivity, 24 diabetes, 25 and family history, or protective factors such as nonsteroidal anti-inflammatory drug use, 26 were not available. Potential confounding by excess alcohol use and tobacco smoking was instead assessed indirectly through exclusion of persons hospitalized for diseases related to alcohol or tobacco.…”
Section: Discussionmentioning
confidence: 99%
“…Inherent adjustments for potential confounding by age, sex, and calendar year were, however, made in the analyses. Direct information on other risk factors, ie, alcohol overconsumption, 22 tobacco smoking, 23 physical inactivity, 24 diabetes, 25 and family history, or protective factors such as nonsteroidal anti-inflammatory drug use, 26 were not available. Potential confounding by excess alcohol use and tobacco smoking was instead assessed indirectly through exclusion of persons hospitalized for diseases related to alcohol or tobacco.…”
Section: Discussionmentioning
confidence: 99%
“…5 Regular physical activity is associated with a lower risk of colon cancer, 8 and likely reduces risk for endometrial cancer 7 and breast cancer in postmenopausal women. 5 Tobacco use can increase risk for CRC, 9 and may modestly increase breast cancer risk based on findings from recent large prospective cohort studies. 10 Fruit and vegetable consumption 5,11 and dietary intake of fat 5 likely have little effect on breast cancer risk.…”
Section: Introductionmentioning
confidence: 99%
“…Of these three cancers, cervical cancer is the only one definitively caused by tobacco use, according to the 2004 Surgeon General's Report on the Health Consequences of Smoking [12]; however, breast and colorectal cancers have also been associated with tobacco use in some evaluations [13,14]. Widely used screening tests are available for all three cancer sites [15].…”
Section: Introductionmentioning
confidence: 99%