Increased Risk of Colorectal Cancer After Obesity Surgery

Validation of Obesity Surgery Data in the Swedish National Patient Registry and Scandinavian Obesity Registry (SOReg)

“…As a result, the short-and longterm effects of such surgery have been examined in a number of studies [1][2][3][4]. Population-based health registers in Sweden are commonly used for research purposes, and validation of these data sources are of importance to ensure research of high reliability and validity [5].…”

Does bariatric surgery reduce cancer risk? A review of the literature

“…of Pages 6 Does bariatric surgery reduce cancer risk? 5 controversy arose with the publication of the article by Derogar et al, 15 which showed a long-term increased risk of colorectal cancer after bariatric surgery. This study has had a significant impact on the bariatric surgery community, becoming an important matter of debate.…”

“…Stratifying by gender, decreased risk in women; RR = 0.68 (95% CI 0.60---0.77), but not in men 0.99 (95% CI 0.74---1.32) Derogar et al 15 Retrospective cohort study of 15 diagnosis. The surgery patients had significantly fewer visits for all cancer diagnoses, suggesting that this type of surgery not only reduces morbidity but also decreases the incidence of malignant disease.…”

“…Different results were obtained in Östlund et al study, 11 in which not only did they found that the risk of breast cancer, as well as the prostate, endometrial and kidney cancer, were not decreased in the bariatric cohort, but they also identified a statistically significantly increased risk of colorectal cancer after surgery. This unexpected finding led the authors to hypothesize that obesity surgery might be associated with increased colorectal cancer risk and they designed a nationwide retrospective cohort study, 15 which concluded that the risk for colorectal cancer increased with time after surgery.…”

Right Colon Carcinoma Infiltrating the Alimentary Limb in a Patient With Biliopancreatic Diversion

“…Moreover, no such increase was found for other obesity-related cancer (breast, kidney, prostate, and endometrium). 21 On the contrary, a cohort study found a 30% decreased risk of colorectal cancer after gastric bypass compared with morbidly obese controls. 22 In some instances BPD needs to be revised as occur in the present case.…”