2005
DOI: 10.1016/j.jcrs.2005.06.039
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Smoking and cataract: Review of causal association

Abstract: Several risk factors for the development of cataract have been identified. This review evaluates epidemiologic literature that has examined tobacco smoking as a risk factor for cataract formation using established causality criteria. Twenty-seven studies were included in this review. Evidence suggests that smoking has a 3-fold increase on the risk for incident nuclear cataract development. There was also evidence of dose response, temporal relationship, and reversibility of effect. There was limited evidence o… Show more

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Cited by 109 publications
(65 citation statements)
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References 47 publications
(118 reference statements)
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“…40,41 Smoking status was also associated with nuclear opacity incidence and progression, which is consistent with a number of previous studies. [42][43][44] We found that current smokers were twice as likely as nonsmokers to have incidence and progression of nuclear cataracts. Past smoking was also related to nuclear opacity incidence, although the relationship was not statistically significant.…”
Section: Discussionmentioning
confidence: 83%
“…40,41 Smoking status was also associated with nuclear opacity incidence and progression, which is consistent with a number of previous studies. [42][43][44] We found that current smokers were twice as likely as nonsmokers to have incidence and progression of nuclear cataracts. Past smoking was also related to nuclear opacity incidence, although the relationship was not statistically significant.…”
Section: Discussionmentioning
confidence: 83%
“…Similar associations have also been found for smoking and the development of age-related macular degeneration 35 and cataract. 36 In our judgement on the balance of the evidence available, particularly from the higher quality studies, there is sufficient evidence of causality and hence justification for educational and smoking cessation interventions with patients and the public who are often unaware that smoking has adverse ocular effects. 37 Patients with Graves' disease should be encouraged to stop smoking in order to both help prevent development of TED and to reduce the general physical harm that smoking causes.…”
Section: Discussionmentioning
confidence: 99%
“…Stopping smoking was associated with a marked, non-linear decrease of the risk of progression to AMD and reduces the risk of developing cataracts [28,29]. Studies suggested a stronger association between smoking [30]. Smoking reduces the supply of antioxidants in our eyes, which may lead to cataracts.…”
Section: Discussionmentioning
confidence: 99%