Smear Conversion, Treatment Outcomes and the Time of Default in Registered Tuberculosis Patients on RNTCP DOTS in Puducherry, Southern India

Vasudevan, Kavita; Jayakumar, Niranjana; Gnanasekaran, Dhivyalakshmi

doi:10.7860/jcdr/2014/8421.4984

Cited by 19 publications

(21 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study we have found 75.2% favourable outcome that is similar to the treatment success rate (71%) of India in retreatment TB cases [ 9 ]. Among the unfavourable outcomes more were defaulter (51.2%) that also collaborate with the Vijay et al (72.8%) and Vasudevan et al (37.6%) study, but in our study, rate of defaulters was quite less than Vijay et al study and quite higher than Vasudevan et al study [ 10 , 11 ]. Though the rate of defaulters was varied widely within India but in all studies it was counted as most common unfavourable outcome.…”

Section: Discussionsupporting

confidence: 86%

Predictors of Treatment Outcome for Retreatment Pulmonary Tuberculosis Cases among Tribal People of an Eastern India District: A Prospective Cohort Study

Saha

2016

Tuberculosis Research and Treatment

View full text Add to dashboard Cite

Objective. The study was conducted to assess the treatment outcome of different category retreatment cases with the aim of finding out the important predictors of unfavorable outcomes. Methodology. This hospital based prospective cohort study was conducted in three tuberculosis units (TUs) of west Midnapore (a district of Eastern India), covering mostly the tribal populated areas. Patients who were registered for Category II antituberculosis treatment between 1st quarter of 2013 (Jan to Mar) and 4th quarter of 2013 (Oct to Dec) were considered as our study cohort and they were followed up till December 2014. The study was started with 177 patients but ultimately ended with 165 patients. Results. Unfavorable outcome was observed among 24.8% patients. Among them mostly 51.2% were defaulter, 22% were failure case, and 26.8% died during treatment. Patients, who were minority by religion, were found 4 times more vulnerable for unfavorable outcome. Unfavorable outcome was found 7 times more common among retreatment TB cases who remain sputum positive after completion of initiation phase of Category II treatment. Conclusion. Programmatic approach should be specified to address the minority by religion population and to reduce the load of sputum positive cases after completion of initiation phase treatment by tracking them.

show abstract

Section: Discussionsupporting

confidence: 86%

Predictors of Treatment Outcome for Retreatment Pulmonary Tuberculosis Cases among Tribal People of an Eastern India District: A Prospective Cohort Study

Saha

2016

Tuberculosis Research and Treatment

View full text Add to dashboard Cite

show abstract

“…This is much lower than the figure reported from New York city in the United States of America (91%) where factors associated with delay in treatment completion were attributed to poor communication, refusal to continue treatment and movement of patients from one site of care to another (11). Our default rate from treatment was 8.1%, versus the WHO target of 4%, and this is slightly lower than that the rate reported in a study in Nigeria (9.1%) (10), but higher than a study in India (7.2%) (12). Causes of default may include older age, smear-negativity, extrapulmonary tuberculosis, rural residence, HIV co-infection and longer treatment regimens (10).…”

Section: Discussioncontrasting

confidence: 71%

Epidemiology of tuberculosis and evaluation of treatment outcomes in the national tuberculosis control programme, River Nile state, Sudan, 2011-2013

Elmadhoun

Noor

Bushara

et al. 2016

East Mediterr Health J

View full text Add to dashboard Cite

Tuberculosis is a major health problem in Sudan, a country that carries 11-15% of the tuberculosis burden in the Eastern Mediterranean Region. This study aimed to describe the epidemiology of tuberculosis in River Nile State and to compare treatment outcomes with WHO recommended indicators. A descriptive study was conducted on data collected from records of 1221 patients registered at tuberculosis management units over the 3 years 2011-2013. The mean age of cases was 37.7 (SD 21.5) years and 65.9% were males; 76.3% were pulmonary tuberculosis and 36.9% were sputum smear-positive cases. Average values for all outcome indicators were suboptimal, notably rates of case notification (30.8 per 100 000), case detection (10.3%), treatment success (79.6%), treatment failure (3.0%), default (8.1%) and death (8.0%). Of the 264 patients tested for HIV, 3.8% were positive. Outcome indicators for the national tuberculosis control programme are lagging behind the required targets. RÉSUMÉ La tuberculose est un problème de santé majeur au Soudan où elle représente 11 à 15 % de la charge de la maladie dans la Région de la Méditerranée orientale. La présente étude avait pour objectif de décrire l'épidémiologie de la tuberculose dans l'État du Nil et de comparer les résultats du traitement à l'aide d'indicateurs recommandés par l'OMS. Une étude descriptive a été menée à partir de données extraites des dossiers de 1221 patients admis dans des unités de prise en charge de la tuberculose sur une période de trois ans (2011)(2012)(2013). L'âge moyen des cas était de 37,7 ans (ET 21,5) et 65,9 % étaient de sexe masculin ; 76,3 % étaient atteints de tuberculose pulmonaire et 36,9 % étaient des cas à frottis positifs. Les valeurs moyennes pour tous les indicateurs de résultats étaient sous-optimales, notamment les taux de notification (30,8 pour 100 000), de dépistage de cas (10,3 %), de guérison (79,6 %), d'échec thérapeutique (3,0 %), d'abandon (8,1 %) et de décès (8,0 %). Sur les 264 patients dépistés pour le VIH, 3,8 % étaient positifs. Les indicateurs de résultats pour le programme national de lutte antituberculeuse accusent un retard par rapport aux objectifs fixés. 2011-

show abstract

“…7 RNTCP has achieved improved cure rates and a success rate of 88% among new smear positive cases was reported in 2011. [8][9][10] The unfavourable outcomes under the RNTCP are death, default and failures. In 2011, death rate, default rate and failure rate among new smear positive cases was reported as 4%, 6% and 2% respectively.…”

mentioning

confidence: 99%

Treatment outcome of tuberculosis patients under directly observed treatment short-course and factors affecting the outcome in tertiary care hospital

Trivedi

Khakhkhar

2019

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

Background: Revised National Tuberculosis Control Programme (RNTCP) based on Directly Observed Treatment Short-course (DOTS) strategy has been made available in entire country by March 2006. Given high rate of unfavourable treatment outcomes reported in some provinces, there is a need to analyse outcomes and identify possible trends and associated risk factors that can help for improvement in RNTCP.Methods: After getting Institutional Ethics Committee (IEC) approval, total of 76 cases diagnosed and treated for Tuberculosis (TB) under Category I of RNTCP were recruited from January to March 2017. All patients were followed up for six months from date of initiating the treatment. The data was obtained from TB treatment register, by patient visit and regular follow-up. The information collected include age and gender of patient, category of treatment, date of treatment initiation, initial sputum conversion, outcome of treatment and date of outcome.Results: Out of total 76 patients, 64 (84.21%) were cured, 5 (6.57%) were lost to follow-up, 4 (5.26%) were failed to treat, 1 (1.32%) patient was died, 1 (1.32%) patient had completed treatment but status was unknown and 1 (1.32%) patient was not evaluated because of transfer. Overall treatment outcome of TB patients under DOTS was matching goal of RNTCP with cure rate of 84.21%.Conclusions: Efforts by DOT providers, adequate patient education, motivating ones in need can bring positive outcomes. In this region, DOTS center is at good working condition in terms of functionality as well as ethically. Gender, age group, residence and initial culture colony did not significantly affect treatment outcome.

show abstract

Smear Conversion, Treatment Outcomes and the Time of Default in Registered Tuberculosis Patients on RNTCP DOTS in Puducherry, Southern India

Cited by 19 publications

References 3 publications

Predictors of Treatment Outcome for Retreatment Pulmonary Tuberculosis Cases among Tribal People of an Eastern India District: A Prospective Cohort Study

Predictors of Treatment Outcome for Retreatment Pulmonary Tuberculosis Cases among Tribal People of an Eastern India District: A Prospective Cohort Study

Epidemiology of tuberculosis and evaluation of treatment outcomes in the national tuberculosis control programme, River Nile state, Sudan, 2011-2013

Treatment outcome of tuberculosis patients under directly observed treatment short-course and factors affecting the outcome in tertiary care hospital

Contact Info

Product

Resources

About