Abstract::
Respiratory viruses have caused many pandemics from past to present and are among
the top global public health problems due to their rate of spread. The recently experienced
COVID-19 pandemic has led to an understanding of the importance of rapid diagnostic tests to prevent
epidemics and the difficulties of developing new vaccines. On the other hand, the emergence
of resistance to existing antiviral drugs during the treatment process poses a major problem for society
and global health systems. Therefore, there is a need for new approaches for the diagnosis,
prophylaxis, and treatment of existing or new types of respiratory viruses. Immunoglobulin Y antibodies
(IgYs) obtained from the yolk of poultry eggs have significant advantages, such as high
production volumes, low production costs, and high selectivity, which enable the development of
innovative and strategic products. Especially in diagnosing respiratory viruses, antibody-based
biosensors in which these antibodies are integrated have the potential to provide superiority in
making rapid and accurate diagnosis as a practical diagnostic tool. This review article aims to provide
information on using IgY antibodies in diagnostic, prophylactic, and therapeutic applications
for respiratory viruses and to provide a perspective for future innovative applications.