SmartArc-Based Volumetric Modulated Arc Therapy for Oropharyngeal Cancer: A Dosimetric Comparison With Both Intensity-Modulated Radiation Therapy and Helical Tomotherapy

Clemente, Stefania; Wu, Binbin; Sanguineti, Giuseppe; Fusco, Vincenzo; Ricchetti, F.; Wong, John W.; McNutt, Todd

doi:10.1016/j.ijrobp.2010.08.007

Cited by 65 publications

(69 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Clemente et al [100] performed a planning study in eight patients with oropharyngeal tumours comparing a nine-field fixed field IMRT (SS), double arc VMAT and HT plan. There was no significant difference in PTV coverage for the high and intermediate dose levels, but the HT plans were better than VMAT and IMRT in the coverage of the elective PTV (D98% was 97.1% in HT plans compared with 94.5% with IMRT and 92.6% with VMAT).…”

Section: Head and Neck Cancermentioning

confidence: 99%

Volumetric modulated arc therapy: a review of current literature and clinical use in practice

Teoh

Clark²,

Wood³

et al. 2011

BJR

565

440

View full text Add to dashboard Cite

ABSTRACT. Volumetric modulated arc therapy (VMAT) is a novel radiation technique, which can achieve highly conformal dose distributions with improved target volume coverage and sparing of normal tissues compared with conventional radiotherapy techniques. VMAT also has the potential to offer additional advantages, such as reduced treatment delivery time compared with conventional static field intensity modulated radiotherapy (IMRT). The clinical worldwide use of VMAT is increasing significantly. Currently the majority of published data on VMAT are limited to planning and feasibility studies, although there is emerging clinical outcome data in several tumour sites. This article aims to discuss the current use of VMAT techniques in practice and review the available data from planning and clinical outcome studies in various tumour sites including prostate, pelvis (lower gastrointestinal, gynaecological), head and neck, thoracic, central nervous system, breast and other tumour sites.

show abstract

Section: Head and Neck Cancermentioning

confidence: 99%

Volumetric modulated arc therapy: a review of current literature and clinical use in practice

Teoh

Clark²,

Wood³

et al. 2011

BJR

565

440

View full text Add to dashboard Cite

show abstract

“…[33][34][35] This, despite the worldwide implementation of this technique, is gradually replacing fixed-field IMRT, thanks to its advantages in terms of treatment efficiency. VMAT planning optimization process is much more complex than fixed-field IMRT.…”

Section: Discussionmentioning

confidence: 99%

“…A few planning studies, [33][34][35] aiming to compare fixed-field IMRT with rotational IMRT and/or tomotherapy, also considered critical swallowing structures in the evaluation of the various techniques' efficacy. Most of the results in these studies are not in agreement with our data as we do find higher average doses to swallowing-related structures.…”

Section: Discussionmentioning

confidence: 99%

Volumetric modulated arc therapy (VMAT) and simultaneous integrated boost in head-and-neck cancer: is there a place for critical swallowing structures dose sparing?

Cilla¹,

Deodato²,

Macchia³

et al. 2016

BJR

View full text Add to dashboard Cite

“…Clemente et al [9] compared IMRT, VMAT and helical tomotherapy for oropharyngeal cancer using SIB. They used three prescription dose levels in their study: 70; 63 and 58.1 Gy to regions of macroscopic, microscopic high risk and microscopic low risk.…”

Section: Discussionmentioning

confidence: 99%

A Feasibility Study of the Dosimetric Compliance Criteria of the NRG-HN002 Head and Neck Clinical Trial Across Different Radiotherapy Treatment Planning Systems and Delivery Techniques: A Model for Optimizing Initial Trial Launch

Giaddui¹

2016

JCPCR

View full text Add to dashboard Cite

The aim of this study was to assess the feasibility of the dosimetric compliance criteria of the NRG-HN002 clinical trial, using different treatment planning systems and different delivery techniques, with the aim of optimizing the initial launch of this national head and neck cancer radiotherapy trial. Five benchmark patients meeting the eligibility criteria for NRG-HN002 were included in this study. Contours for target volumes and organ at risks were drawn according to the study guidelines. Two IMRT and two VMAT plans were developed for each patient using Varian Eclipse and the auto-planning module in Philips Pinnacle. Dose volume histograms of the plans were analyzed and compared using MIM software and tested against the compliance criteria of the protocol. All dosimetric compliance criteria were met using the two treatment planning systems and delivery techniques, except the maximum dose for PTV_4800 when it overlapped with higher dose PTVs. The coverage for the three PTVs (PTV_6000, PTV_5400 and PTV_4800) was achieved and also the PTV maximum doses were not exceeded in both IMRT and VMAT plans. The average maximum dose in all plans for SpinalCord_05, Spinal Cord and BrainStem_03 were 45 ± 4 Gy, 40 ± 5 Gy and 30 ± 9 Gy. Recommended dose values for other OARs (Parotid_Contra, larynx, pharynx, Sub Mandibular_Contra, Oral Cavity, Esophagus_Up, Mandible and NonPTV) were also achieved with minor deviations in very few occasions. The maximum dose of PTV_4800 criterion was removed from the protocol based on the results of this study. For radiotherapy-based clinical trials, this feasibility testing process is a model for reducing planning deviations and the necessity for amendments to the dosimetric criteria subsequent to activation. Keywords

show abstract

SmartArc-Based Volumetric Modulated Arc Therapy for Oropharyngeal Cancer: A Dosimetric Comparison With Both Intensity-Modulated Radiation Therapy and Helical Tomotherapy

Cited by 65 publications

References 30 publications

Volumetric modulated arc therapy: a review of current literature and clinical use in practice

Volumetric modulated arc therapy: a review of current literature and clinical use in practice

Volumetric modulated arc therapy (VMAT) and simultaneous integrated boost in head-and-neck cancer: is there a place for critical swallowing structures dose sparing?

A Feasibility Study of the Dosimetric Compliance Criteria of the NRG-HN002 Head and Neck Clinical Trial Across Different Radiotherapy Treatment Planning Systems and Delivery Techniques: A Model for Optimizing Initial Trial Launch

Contact Info

Product

Resources

About