Smart functionalized thin gel layers for electrochemical sensors, biosensors and devices

Stimuli-responsive polymers for interface engineering toward enhanced electrochemical analysis of neurochemicals

“…In other words, microgels are sensitive to their environment. [72][73][74] Because of the unique properties to undergo fast and reversible phase transitions, recently, the interest in the construction of microgel-based biosensors have significantly increased. For example, the horseradish peroxidase (HRP)-polyacrylamide (PAA)-based biosensor has been successfully used for amperometric determination of acetaminophen (APAP).…”

A novel self-healing hydrogel based on derivatives of natural α-amino acids with potential applications as a strain sensor

“…Hydrogels may possess remarkable features -such as selfhealing ability, [1][2][3] responsiveness to external stimuli, 4,5 and degradability under strictly defined conditions -which make them attractive for use as ''smart'' materials, including in drug delivery systems, electrochemistry, sensors and biosensors, wound dressing, coating, etc. [6][7][8][9] The class of self-healing hydrogels has received much attention in the past few years, due to their remarkable ability to restore nearly all of their original properties after experiencing damage. Such materials require reversible dynamic bonds (including non-covalent and covalent bonds) in order to be able to undergo a self-healing process after damage, cracking, or deformation, hence extending lifespans and lowering costs.…”

“…Hydrogels may possess remarkable features – such as self-healing ability, 1–3 responsiveness to external stimuli, 4,5 and degradability under strictly defined conditions – which make them attractive for use as “smart” materials, including in drug delivery systems, electrochemistry, sensors and biosensors, wound dressing, coating, etc. 6–9…”

Constructing a Facile Biocomputing Platform Based on Smart Supramolecular Hydrogel Film Electrodes with Immobilized Enzymes and Gold Nanoclusters

“…Recently, great efforts and instructive ideas have been put forward to develop sophisticated biorelated logic gates on a single identical platform. , Multiple stimulus-responsive films are widely used as smart matrices in the construction of biomolecular logic systems with various functions . For example, it is a feasible approach to increase the number of input signals in biologic networks simply by copolymerization of several different stimuli-responsive materials into polymer film electrodes ,− or combining diverse smart films into multilayer electrodes. , In view of the booming fluorescent biosensing, another constructive pathway is to increase the number of output signals by embedding fluorescent nanomaterials , or coordination lanthanide ions , into stimuli-switchable polymer films.…”