Smart dental materials for antimicrobial applications

Montoya, Carolina; Roldán, Lina María Colmenares; Yu, Michelle; Valliani, Sara; Ta, Christina; Yang, Maobin; Orrego, Santiago

doi:10.1016/j.bioactmat.2022.12.002

Cited by 33 publications

(27 citation statements)

References 341 publications

(391 reference statements)

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“…The development of stimuli-responsive chitosan-based materials in dentistry has gained interest over the past decades due to the urgency to treat oral disease with minimum invasive surgery and promote teeth as well as alveolar bone regeneration. 186 In addition, the development of a chitosanbased smart biomaterial plays an important role in guided tissue regeneration, localized controlled drug release, smart antibacterial properties, and noninvasive periodontic treatment.…”

Section: Chitosan-basedmentioning

confidence: 99%

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

Budiarso,

Rini,

Tsalsabila

et al. 2023

ACS Biomater. Sci. Eng.

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Over the past decade, smart and functional biomaterials have escalated as one of the most rapidly emerging fields in the life sciences because the performance of biomaterials could be improved by careful consideration of their interaction and response with the living systems. Thus, chitosan could play a crucial role in this frontier field because it possesses many beneficial properties, especially in the biomedical field such as excellent biodegradability, hemostatic properties, antibacterial activity, antioxidant properties, biocompatibility, and low toxicity. Furthermore, chitosan is a smart and versatile biopolymer due to its polycationic nature with reactive functional groups that allow the polymer to form many interesting structures or to be modified in various ways to suit the targeted applications. In this review, we provide an up-to-date development of the versatile structures of chitosan-based smart biomaterials such as nanoparticles, hydrogels, nanofibers, and films, as well as their application in the biomedical field. This review also highlights several strategies to enhance biomaterial performance for fast growing fields in biomedical applications such as drug delivery systems, bone scaffolds, wound healing, and dentistry.

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Section: Chitosan-basedmentioning

confidence: 99%

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

Budiarso,

Rini,

Tsalsabila

et al. 2023

ACS Biomater. Sci. Eng.

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“…Antibacterial surfaces include antibiotic, nano-silver, photocatalytic, nano-, bionic and smart bioresponsive antibacterial coatings [ 86 , 161 ] which produce different antibacterial effects [ 161 ]. Research on the construction of antimicrobial surfaces for zirconia abutments is still lacking.…”

Section: Surface Modification Of Zirconia Abutmentsmentioning

confidence: 99%

The integration of peri-implant soft tissues around zirconia abutments: Challenges and strategies

Tang

Luo

Zhou

et al. 2023

Bioactive Materials

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“…An example of these implants is the bioactive glass-based coating that promoted antimicrobial effects designed by the working group of Barão. , The functionalization of the implant surface with nanoparticles of other compounds such as ZnO, Mg, and Si has been observed to present an improvement in osteoinduction and a biofilm-reducing effect of opportunistic pathogens such as Candida albicans , Staphylococcus aureus , Streptococcus mutans , and Pseudomonas aeruginosa . Other carriers for antimicrobial agents that continue to be developed include nanocapsules, liposomes, micelles, and nanofibers; the latter have a high load capacity due to their large contact surface and allow the release of the antimicrobial in a controlled manner depending on the erosion of the biopolymer of which it is composed, improving the effectiveness of the treatment …”

Section: Applications In Dentistrymentioning

confidence: 99%

“…26 Other carriers for antimicrobial agents that continue to be developed include nanocapsules, liposomes, micelles, and nanofibers; the latter have a high load capacity due to their large contact surface and allow the release of the antimicrobial in a controlled manner depending on the erosion of the biopolymer of which it is composed, improving the effectiveness of the treatment. 27 The current development of dental implants has the goal of creating smart biomaterial implants that have the ability to release the antimicrobial agent in response to stimuli from the microenvironment where the implant is located; stimuli such as pH changes, light, and enzymatic activity, among others. 28,29 Liang's working group observed the long-term antibacterial effects of a dental adhesive resin containing dodecylmethylaminoethyl methacrylate in the presence of an acidic environment (pH < 6).…”

Section: Applications In Dental Implantmentioning

confidence: 99%

The Era of Biomaterials: Smart Implants?

Silva-López

Alcántara-Quintana

2023

ACS Appl. Bio Mater.

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Conditions, accidents, and aging processes have brought with them the need to develop implants with higher technology that allow not only the replacement of missing tissue but also the formation of tissue and the recovery of its function. The development of implants is due to advances in different areas such as molecular-biochemistry (which allows the understanding of the molecular/cellular processes during tissue repair), materials engineering, tissue regeneration (which has contributed advances in the knowledge of the properties of the materials used for their manufacture), and the so-called intelligent biomaterials (which promote tissue regeneration through inductive effects of cell signaling in response to stimuli from the microenvironment to generate adhesion, migration, and cell differentiation processes). The implants currently used are combinations of biopolymers with properties that allow the formation of scaffolds with the capacity to mimic the characteristics of the tissue to be repaired. This review describes the advances of intelligent biomaterials in implants applied in different dental and orthopedic problems; by means of these advances, it is expected to overcome limitations such as additional surgeries, rejections and infections in implants, implant duration, pain mitigation, and mainly, tissue regeneration.

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Smart dental materials for antimicrobial applications

Cited by 33 publications

References 341 publications

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

Chitosan-Based Smart Biomaterials for Biomedical Applications: Progress and Perspectives

The integration of peri-implant soft tissues around zirconia abutments: Challenges and strategies

The Era of Biomaterials: Smart Implants?

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