Small margin excision of periocular basal cell carcinoma: 5 year results

Hsuan, J D; Harrad, R A; Potts, M J; Collins, C. D.

doi:10.1136/bjo.2003.018531

Cited by 64 publications

(54 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…15 In addition, it may not be available in every hospital. It is reassuring that our technique of excising BCC and examining with rapid turnover paraffin techniques, occasionally combined with fresh-frozen section control, achieves results comparable to another recent study.…”

Section: Discussionmentioning

confidence: 99%

5 Years review of periocular basal cell carcinoma and proposed follow-up protocol

Brown

Bamford

et al. 2012

Eye

View full text Add to dashboard Cite

In all, 67% were nodular BCC and 45.4% located in the lower eyelid. The main outcome measure was the recurrence rate. None of the patients with primary nodular BCC suffered recurrence. The recurrence rate for primary morphoeaform BCC following complete excision is 3.8%. In total, 8.1% of patients had several lesions simultaneously whereas 7.8% patients had BCC in multiple locations subsequently (metachronous). Three patients who had previously recurrent BCC (rBCC) treated elsewhere or not using this method had orbital/lacrimal drainage system involvement requiring exenteration. Conclusion We recommend that patients with a single, completely excised primary solid or nodular BCC can be discharged after one 6-monthly review, although they should be instructed to monitor for the development of further lesions. The incidence of recurrence for primary morphoeaform BCC is 3.8% and for rBCC is 3.6% over 5 years and these patients should stay under review for this period.

show abstract

Section: Discussionmentioning

confidence: 99%

5 Years review of periocular basal cell carcinoma and proposed follow-up protocol

Brown

Bamford

et al. 2012

Eye

View full text Add to dashboard Cite

show abstract

“…15 Nevertheless, it is important to preserve as much normal tissue as possible, particularly in the periocular region, thus optimizing the possibility of achieving good esthetic results with minimal intervention. 16 With the objective of preserving tissue, while avoiding reoperating an incompletely excised periorbital BCC, the present study evaluated whether residual tumor tissue is indicative of tumor recurrence, what the risk factors for recurrence are, and the most probable timing of a diagnosis of recurrence, in order to ensure that only those for whom reoperation is mandatory are subjected to further surgery.…”

Section: Introductionmentioning

confidence: 99%

Does incomplete excision of basal cell carcinoma of the eyelid mean tumor recurrence?

Jankovic

Kovačević

Visnjic

et al. 2010

An. Bras. Dermatol.

View full text Add to dashboard Cite

Introduction: Basal cell carcinoma is the most common tumor of the eyelid. In this region, reconstruction is complex and damage to healthy tissue should be minimal. Objective: To define the relationship between margin clearance at excision and the recurrence rate of basal cell carcinoma of the eyelid. Methods: This prospective study was conducted with 111 patients submitted to surgery for basal cell carcinoma of the eyelid between 2001 and 2003 and followed up for a period of five years. The patients were evaluated according to age, tumor site, recurrence rate and margin clearance at excision. Results: No significant association was found between incomplete tumor excision and recurrence except in patients under 56 years of age, female patients and in the case of tumors of the medial canthus. Conclusion: A risk of recurrence in incompletely excised basal cell carcinomas of the eyelid was only confirmed in younger patients, females and for tumors of the medial canthus. Keywords: Basal cell carcinoma; eyelid; recurrence.Resumo: Introdução: O carcinoma basocelular é o tumor mais comum entre os tumores das pálpebras. Nesta região, a reconstrução é complexa e recomenda-se que haja perda mínima de tecido saudável. Objetivo: Para definir a relação entre margem livre de tumor na excisão e taxa de recidiva do carcinoma basocelular das pálpebras. Métodos: Este estudo prospectivo incluiu 111 pacientes operados para remoção de carcinoma basocelular das pálpebras no período de 2001 a 2003, com acompanhamento subsequente de 5 anos. Os pacientes foram avaliados de acordo com a idade, localização do tumor, taxa de recidiva, e margem livre de tumor na excisão. Resultados: Não se encontrou associação significativa entre a excisão incompleta do tumor e casos de recidiva, exceto em pacientes com idade inferior a 56 anos, pacientes do sexo feminino e em tumores do canto medial. Conclusão: Um risco maior de recidiva de carcinoma basocelular das pálpebras com excisão incompleta foi confirmado estatisticamente apenas em pacientes mais jovens, em mulheres, e nos tumores do canto interno.

show abstract

“…Hamada reported repair by direct closure in 72% of the cases with excellent functional and cosmetic results (10). Hsuan found the same in 34.5% of cases (12). The aesthetic result is also a very important issue in surgical excision of the BCC.…”

Section: Discussionmentioning

confidence: 93%

“…In our unit in Varna, Bulgaria we use the former. It is debatable in the literature, but general appreciation is that paraffin sections are histologically superior to frozen section, with better preservation of detail on examination (7,12). Ghauri et al found that 5% of tumors reported as having clear margins on frozen section were seen later to have involved margins on permanent section (8).…”

mentioning

confidence: 99%

“…Ra-diotherapy, cryoterapy, laser ablation, photodynamic therapy, chemotherapy, and immunotherapy have all been described and may be useful for inoperable or widespread disease. The complete surgical excision of BCC of the eyelid remains the "gold" standard of treatment and excellent results are obtained if the tumor is completely removed (12). In their evidence-based update regarding treatment options of basal cell carcinoma, Cook and Bartley conclude that Mohs' micrographic surgery (MMS) and excision with frozen-section or permanent-section control yield the highest cure rate and lowest frequency of recurrence (3).…”

mentioning

confidence: 99%

See 1 more Smart Citation